Spots Global Cancer Trial Database for Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

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Trial Identification

Brief Title: Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

Official Title: Molecular Correlates of Sensitivity and Resistance to Therapy in Genitourinary Malignancy

Study ID: NCT01050504

Conditions

Localized Renal Pelvis and Ureter Urothelial Carcinoma

Malignant Solid Neoplasm

Metastatic Malignant Neoplasm in the Bone

Metastatic Malignant Neoplasm in the Soft Tissues

Metastatic Renal Pelvis and Ureter Urothelial Carcinoma

Recurrent Bladder Carcinoma

Recurrent Prostate Carcinoma

Recurrent Renal Pelvis and Ureter Urothelial Carcinoma

Stage IV Bladder Cancer AJCC v7

Stage IV Bladder Urothelial Carcinoma AJCC v7

Stage IV Prostate Cancer AJCC v7

Interventions

Cytology Specimen Collection Procedure

Laboratory Biomarker Analysis

Study Description

Brief Summary: This study collects and studies tissue and blood samples from patients with prostate or bladder/urothelial cancer that has recurred (come back) at or near the same place as the original (primary) tumor or has spread to other parts of the body. Studying samples of blood and tissue samples from patients with prostate or bladder/urothelial cancer in the laboratory may help doctors learn more about new biomarkers, potential drug targets, and resistance developing in response to treatment. It may also help doctors find better ways to treat the cancer.

Detailed Description: OUTLINE: Patients undergo collection of blood and tissue samples for analysis via mutation mapping, DNA sequencing, gene expression microarray, and gene profiling.