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Brief Title: Ociperlimab With Tislelizumab and Chemotherapy in Participants With Untreated Metastatic Non-Small Cell Lung Cancer
Official Title: AdvanTIG-205: A Phase 2, Randomized Study of Ociperlimab (BGB-A1217) and Tislelizumab With Chemotherapy in Patients With Previously Untreated Locally Advanced, Unresectable, or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study ID: NCT05014815
Brief Summary: This is a randomized investigator and participant blinded, sponsor unblinded, multicenter study that evaluates the safety and efficacy of ociperlimab with tislelizumab and histology-based chemotherapy compared with treatment with tislelizumab and histology-based chemotherapy in participants with previously untreated locally advanced, unresectable, or metastatic NSCLC
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Valkyrie Clinical Trials, Los Angeles, California, United States
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
Comprehensive Cancer Center of Nevada, Henderson, Nevada, United States
Northwell Health-Monter Cancer Center, Lake Success, New York, United States
Xcancer_Dayton Physician Network, Dayton, Ohio, United States
Tennessee Cancer Specialist, Knoxville, Tennessee, United States
Texas Oncology (Tyler) - USOR, Tyler, Texas, United States
Cancer Care Northwest, Spokane Valley, Washington, United States
Northern Beaches Hospital, Frenchs Forest, New South Wales, Australia
Port Macquarie Base Hospital, Port Macquarie,, New South Wales, Australia
Townsville University Hospital, Douglas, Queensland, Australia
Toowoomba Hospital, Toowoomba, Queensland, Australia
Peninsula & South Eastern Hematology and Oncology Group, Frankston, Victoria, Australia
Olivia Newton-John Cancer Wellness & Research Centre, Heidelberg, Victoria, Australia
Universitätsklinikum Krems, Krems, Krems An Der Donau, Austria
China-Japan Friendship Hospital, Beijing, Beijing, China
Beijing Cancer Hospital, Beijing, Beijing, China
Xin Qiao Hospital Affiliated to The Army Medical University, Chongqing, Chongqing, China
Army Medical Center of PLA, Chongqing, Chongqing, China
Fujian Cancer Hospital, Fujian, Fujian, China
First Hospital of Lanzhou University, Lanzhou, Gansu, China
Cancer Center of Guangzhou Medical University, Guangzhou, Guangdong, China
Affiliated Tumor Hospital of Harbin Medical University, Harbin, Heilongjiang, China
First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
Jingzhou Central Hospital, Jingzhou, Hubei, China
Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, China
Chenzhou First People's Hospital, Chenzhou, Hunan, China
Changzhou Cancer Hospital, Changzhou, Jiangsu, China
Ansteel Group General Hospital, Anshan, Liaoning, China
Shandong Cancer Hospital, Jinan, Shandong, China
Liaocheng People's Hospital, Liaocheng, Shandong, China
Fudan university Shanghai Cancer Center, Shanghai, Shanghai, China
Huashan hospital affiliated to Fudan University, Shanghai, Shanghai, China
Shanghai Pulmonary Hospital, Shanghai, Shanghai, China
West China Hospital ,Sichuan University, Chengdu, Sichuan, China
The First People's Hospital of Kashgar, Kashgar, Xinjiang, China
First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, Xinjiang, China
Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China
Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China
Huzhou Central Hospital, Huzhou, Zhejiang, China
The First Hospital of Jiaxing, Jiaxing, Zhejiang, China
Jinhua Municipal Central Hospital, Jinhua, Zhejiang, China
Hôpital Européen Georges Pompidou, Paris, Cedex, France
Hopital Charles Nicolle - Centre Hospitalier Universitaire de Rouen, Rouen, Cedex, France
Institut Curie, Paris, , France
Gangnam Severance Hospital, Yonsei University Health System, Seoul, Gangnam-Gu, Korea, Republic of
Dong-A University Hospital, Busan, , Korea, Republic of
CHA Bundang Medical Center, CHA University, Gyeonggi-do, , Korea, Republic of
Ajou University Hospital, Gyeonggi-do, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Kangbuk Samsung Hospital, Seoul, , Korea, Republic of
Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Korea University Guro Hospital, Seoul, , Korea, Republic of
Ulsan University Hospital, Ulsan, , Korea, Republic of
Hospital Universitario Central de Asturias, Oviedo, Austrias, Spain
Consorcio Hospitalario Provincial de Castellón, Castillón, Comunidad De Valencia, Spain
Instituto Valenciano de Oncologia-IVO, Valencia, Comunidad De Valencia, Spain
Hospital Universitario de León, León, Leon, Spain
Centro Oncológico de Galicia, A Coruña, , Spain
MD Anderson Cancer Center - Madrid, Madrid, , Spain