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Brief Title: Study Of Candonilimab Combined With Radiotherapy In The Treatment of Locally Advanced Cervical Cancer
Official Title: A Single-arm, Multicenter, Phase II Study to Evaluate Candonilimab(AK104) Combined With Radiotherapy For The Treatment of Locally Advanced Cervical Cancer
Study ID: NCT05687851
Brief Summary: Candonilimab(AK104)is a humanized IgG1 bispecific antibody that targets PD-1 and CTLA-4. This is a single-arm, multicenter, open-label, phase II study, the purpose of this study is to evaluate the efficacy and safety of candonilimab plus radiotherapy in participants with locally advanced cervical cancer who do not tolerate chemotherapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Chongqing university Cancer Hospital, Chongqing, CHN, China
Name: Qi Zhou, MD
Affiliation: Chongqing University Cancer Hospital
Role: PRINCIPAL_INVESTIGATOR