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Brief Title: Phase I Endovenous Administration of Oncolytic Adenovirus ICOVIR-5 in Patients With Advanced or Metastatic Melanoma
Official Title: Phase I Clinical Trial of Endovenous Administration of Conditionally Replicative Adenovirus ICOVIR-5 in Patients With Locally Advanced or Metastatic Melanoma
Study ID: NCT01864759
Brief Summary: The investigators will evaluate the safety of a single endovenous infusion of ICOVIR5 in adults with locally advanced and metastatic melanoma. ICOVIR5 consists in a conditionally replicative or oncolytic adenovirus.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Institut Català d'Oncologia - L'Hospitalet, L'Hospitalet del Llobregat, Barcelona, Spain
Name: Ramon Salazar, MD PhD
Affiliation: Institut Català d'Oncologia
Role: PRINCIPAL_INVESTIGATOR
Name: Ramon Alemany, PhD
Affiliation: Institut Català d'Oncologia
Role: STUDY_CHAIR