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Brief Title: A Phase 1 Study of Safety and Bioactivity With FG-3019 in Combination With Gemcitabine and Erlotinib for Subjects With Locally Advanced or Metastatic Pancreatic Cancer
Official Title: A Phase 1 Study of Safety and Bioactivity With FG-3019 in Combination With Gemcitabine and Erlotinib for Subjects With Locally Advanced or Metastatic Pancreatic Cancer
Study ID: NCT01181245
Brief Summary: Objectives * Primary: To evaluate the safety and tolerability of FG-3019 in combination with gemcitabine and erlotinib * Secondary: To evaluate the efficacy and pharmacokinetics of FG-3019 in combination with gemcitabine and erlotinib
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Stanford University School of Medicine, Stanford, California, United States
Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States
University Hospitals of Cleveland, Case Comprehensive Cancer Center, Cleveland, Ohio, United States
Oregon Health Sciences University (OHSU), Portland, Oregon, United States
University of Pennsylvania, Philadelphia, Pennsylvania, United States
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
Virginia Mason Medical Center, Seattle, Washington, United States
Name: Albert C Koong, MD, PhD
Affiliation: Stanford University
Role: PRINCIPAL_INVESTIGATOR
Name: J. Marc Pipas, MD
Affiliation: Dartmouth-Hitchcock Medical Center
Role: PRINCIPAL_INVESTIGATOR
Name: Vincent J Picozzi, MD, PhD
Affiliation: Virginia Mason Hospital/Medical Center
Role: PRINCIPAL_INVESTIGATOR
Name: Peter J O'Dwyer, MD
Affiliation: University of Pennsylvania
Role: PRINCIPAL_INVESTIGATOR
Name: Smitha Krishnamurthi, MD
Affiliation: University Hospitals of Cleveland, Case Comprehensive Cancer Center
Role: PRINCIPAL_INVESTIGATOR
Name: Charles Lopez, MD
Affiliation: Oregon Health and Science University
Role: PRINCIPAL_INVESTIGATOR
Name: Nathan Bahary, MD
Affiliation: University of Pittsburgh
Role: PRINCIPAL_INVESTIGATOR