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Brief Title: A Phase 1b/2 Study of Rebastinib (DCC-2036) in Combination With Paclitaxel in Patients With Advanced or Metastatic Solid Tumors
Official Title: An Open-Label, Multicenter, Phase 1b/2 Study of Rebastinib (DCC-2036) in Combination With Paclitaxel to Assess Safety, Tolerability, and Pharmacokinetics in Patients With Advanced or Metastatic Solid Tumors
Study ID: NCT03601897
Brief Summary: This is an open-label Phase 1b/2 multicenter study of rebastinib (DCC-2036) in combination with paclitaxel designed to evaluate the safety, tolerability, and pharmacokinetics (PK) in patients with advanced or metastatic solid tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Alabama Comprehensive Cancer Center, Birmingham, Alabama, United States
University of Colorado Denver- Anschutz Medical Center, Aurora, Colorado, United States
Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States
The University of Kansas Clinical Research Center, Kansas City, Kansas, United States
Dana-Farber, Boston, Massachusetts, United States
Montefiore Medical Center, Bronx, New York, United States
Northwell Health/Monter Cancer Center, Lake Success, New York, United States
Ohio State University Wexner Medical Center, Columbus, Ohio, United States
University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
Women & Infants Hospital, Providence, Rhode Island, United States
Sarah Cannon Research Institute, Nashville, Tennessee, United States
MD Anderson Cancer Center, Houston, Texas, United States
Oncology Consultants- Texas Medical Center, Houston, Texas, United States