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Spots Global Cancer Trial Database for TNFerade Biologic to Treat Locally Advanced Prostate Cancer

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: TNFerade Biologic to Treat Locally Advanced Prostate Cancer

Official Title: A PHASE I SAFETY AND TOLERABILITY TRIAL OF RADIOTHERAPY, ANDROGEN DEPRIVATION, AND INTRATUMORAL INJECTIONS OF AdGVEGR.TNF.11D (TNFeradeTM) FOR PATIENTS WITH LOCALLY ADVANCED PROSTATE CANCER

Study ID: NCT01048151

Study Description

Brief Summary: While radiation therapy with androgen ablation (hormone reduction) is the standard method of treating locally advanced prostate cancer. New treatments are being combined with radiation therapy in an effort to further improve the cure rates. This study proposes to combine an experimental drug, TNFerade™ Biologic, (also called AdGVEGR.TNF.11D or "TNFerade") at different dose (amounts) levels in combination with radiation. TNFerade™ Biologic is a form of gene transfer therapy that when injected into the tumor has shown to increase the effect of radiation therapy.

Detailed Description:

Eligibility

Minimum Age:

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: MALE

Healthy Volunteers: No

Locations

University of Chicago, Chicago, Illinois, United States

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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