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Brief Title: Phase 1/2 Study of OBI-999 in Patients With Advanced Solid Tumors
Official Title: A Phase 1/2, Open-Label, Dose-Escalation and Cohort-Expansion Study Evaluating the Safety, Pharmacokinetics, and Therapeutic Activity of OBI-999 in Patients With Advanced Solid Tumors
Study ID: NCT04084366
Brief Summary: The purpose of this study is to establish the maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of OBI-999 as monotherapy, and to characterize the safety and preliminary clinical activity profile of the RP2D of OBI-999 in patients with advanced solid tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Scripps MD Anderson Cancer Center, La Jolla, California, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
West Cancer Center, Germantown, Tennessee, United States
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Name: Apostolia Tsimberidou, MD, PhD
Affiliation: M.D. Anderson Cancer Center
Role: PRINCIPAL_INVESTIGATOR