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Brief Title: Changes in Tumor Tissue and Serum Biomarkers Before and After Cetuximab Combined With Preoperative Radiotherapy in Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
Official Title: Changes in Tumor Tissue and Serum Biomarkers Before and After Cetuximab Combined With Preoperative Radiotherapy in Locally Advanced Middle or Lower Thoracic Esophageal Squamous Cell Carcinoma
Study ID: NCT02123381
Brief Summary: This study aim to investigate Changes in tumor tissue and serum biomarkers before and after cetuximab combined with preoperative radiotherapy in locally advanced thoracic middle-lower segment esophageal squamous cell carcinoma.We want to find one or more effective biomarkers to predict and evaluate the patients who will be benefit from cetuximab combined with preoperative radiotherapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Sichuan Cancer Hospital & Institute, Chengdu, Sichuan, China
Name: YONGTAO HAN, MD, PhD
Affiliation: Sichuan Cancer Hospital & Institute
Role: PRINCIPAL_INVESTIGATOR
Name: GE WANG, MD, PhD
Affiliation: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Role: PRINCIPAL_INVESTIGATOR
Name: TAIQIAN GONG, MD, PhD
Affiliation: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Role: PRINCIPAL_INVESTIGATOR
Name: LONG CHEN, MD, PhD
Affiliation: Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Role: PRINCIPAL_INVESTIGATOR
Name: NAIQUAN MAO, MD, PhD
Affiliation: Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Role: PRINCIPAL_INVESTIGATOR
Name: ZHIHUA RUAN, MD, PhD
Affiliation: Southwest Hospital, China
Role: PRINCIPAL_INVESTIGATOR
Name: GANG XIONG, MD, PhD
Affiliation: Southwest Hospital, China
Role: PRINCIPAL_INVESTIGATOR
Name: JIANGUO SUN, MD, PhD
Affiliation: Xinqiao Hospital of Chongqing
Role: PRINCIPAL_INVESTIGATOR
Name: GUANGHUI LI, MD.PHD
Affiliation: Xinqiao Hospital of Chongqing
Role: PRINCIPAL_INVESTIGATOR
Name: DEZHI LI, MD, PhD
Affiliation: Xinqiao Hospital of Chongqing
Role: PRINCIPAL_INVESTIGATOR
Name: MINGZHANG XIANG, MD,PhD
Affiliation: Xinqiao Hospital of Chongqing
Role: PRINCIPAL_INVESTIGATOR