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Spots Global Cancer Trial Database for The BEACON Study (Breast Cancer Outcomes With NKTR-102)

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Trial Identification

Brief Title: The BEACON Study (Breast Cancer Outcomes With NKTR-102)

Official Title: The BEACON Study (Breast Cancer Outcomes With NKTR-102): A Phase 3 Open-Label, Randomized, Multicenter Study of NKTR-102 Versus Treatment of Physician's Choice (TPC) in Patients With Locally Recurrent or Metastatic Breast Cancer Previously Treated With an Anthracycline, a Taxane and Capecitabine

Study ID: NCT01492101

Study Description

Brief Summary: The study is designed as an open-label, randomized, parallel, two arm, multicenter, international Phase 3 study in patients with recurrent or metastatic breast cancer previously treated with cytotoxic chemotherapy regimens. The primary study objective is to compare overall survival of patients who receive NKTR-102 given once every 21 days to patients who receive treatment of Physician's Choice selected from a list of seven single-agent intravenous therapies.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Arizona Oncology Associates, PC - NAHOA, Flagstaff, Arizona, United States

Providence Health System - Southern California d/b/a Roy and Patricia Disney Family Cancer Center, Burbank, California, United States

University of Southern California, Los Angeles, California, United States

PMK Medical Group, Inc., DBA Ventura County Hematology Oncology Specialists, Oxnard, California, United States

Wilshire Oncology Medical Group, Inc., Pasadena, California, United States

Desert Hematology Oncology Medical Group, Rancho Mirage, California, United States

University of California San Francisco, San Francisco, California, United States

Stanford University School of Medicine, Stanford, California, United States

Kaiser Permanente, Vallejo, California, United States

Rocky Mountain Cancer Centers, Denver, Colorado, United States

Pre clinical Science Bldg LR3, Washington, District of Columbia, United States

Medstar, Washington, District of Columbia, United States

Mayo Clinic in Florida, Jacksonville, Florida, United States

University of Miami School of Medicine, Miami, Florida, United States

Advanced Medical Specialties, Miami, Florida, United States

Florida Cancer Research Institute, Plantation, Florida, United States

Hematology Oncology Associates of the Treasure Coast, Port Saint Lucie, Florida, United States

Northeast Georgia Cancer Care, Athens, Georgia, United States

Peachtree Hematology Oncology Consultants, Atlanta, Georgia, United States

Emory University, Atlanta, Georgia, United States

Central Georgia Cancer Care, Macon, Georgia, United States

Northwest Georgia Oncology Centers, P.C., Marietta, Georgia, United States

Summit Cancer Care, P.C., Savannah, Georgia, United States

The University of Chicago Medicine, Chicago, Illinois, United States

Oncology Specialists, Niles, Illinois, United States

Illinois Cancer Care, P.C., Peoria, Illinois, United States

IU Health Simon Cancer Center, Indianapolis, Indiana, United States

Hall-Perrine Cancer Center, 3rd Floor, Cedar Rapids, Iowa, United States

Kansas City Cancer Center, Overland Park, Kansas, United States

Louisville Oncology Clinical Research Program, Louisville, Kentucky, United States

Maryland Oncology Hematology, P.A., Columbia, Maryland, United States

Minnesota Oncology Hematology, P.A., Minneapolis, Minnesota, United States

University of Minnesota, Minneapolis, Minnesota, United States

Mayo Clinic, Rochester, Minnesota, United States

Coborn Cancer Center, Saint Cloud, Minnesota, United States

Missouri Cancer Associates, Columbia, Missouri, United States

Washington University in St. Louis, Saint Louis, Missouri, United States

Missouri Baptist Medical Center, Saint Louis, Missouri, United States

Frontier Cancer Center and Blood Institute, Billings, Montana, United States

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States

Hematology-Oncology Associates of Northern NJ, PA, Morristown, New Jersey, United States

The cancer Institute of New Jersey, New Brunswick, New Jersey, United States

Cooper University Hospital, Voorhees, New Jersey, United States

UNM Cancer Center, Albuquerque, New Mexico, United States

New York Oncology Hematology, P.C., Albany, New York, United States

Monte fiore, Bronx, New York, United States

Sciode Medical Associates, PLLC, d.b.a. Eastchester Center for Cancer Care, Bronx, New York, United States

Beth Israel Medical Center, New York, New York, United States

Cornell University, New York, New York, United States

SUNY Upstate Medical University, Syracuse, New York, United States

Carolinas Hematology Oncology Associates, Charlotte, North Carolina, United States

DUMC, Duke South, Durham, North Carolina, United States

Sanford Research/USD, Fargo, North Dakota, United States

University of Cincinnati, Cincinnati, Ohio, United States

Comprehensive Breast Cancer, Columbus, Ohio, United States

Signal Point Clinical Research Center, Middletown, Ohio, United States

Northwest Cancer Specialists, P.C., Portland, Oregon, United States

Medical Oncology Associates of Wyoming Valley, PC, Kingston, Pennsylvania, United States

Cancer Centers of the Carolinas, Easley, South Carolina, United States

Sanford Research/USD, Sioux Falls, South Dakota, United States

The West Clinic, Memphis, Tennessee, United States

Sarah Cannon Research Institute (SCRI), Nashville, Tennessee, United States

Sarah Cannon Research Institute, Nashville, Tennessee, United States

Texas Oncology-Abilene, Abilene, Texas, United States

Texas Oncology-Austin Midtown, Austin, Texas, United States

Texas Oncology-Beaumont, Mamie McFaddin Ward Cancer Center, Beaumont, Texas, United States

Texas Oncology-Bedford, Bedford, Texas, United States

Texas Oncology-Medical City Dallas, Dallas, Texas, United States

Texas Oncology-Dallas Presbyterian Hospital, Dallas, Texas, United States

Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, Texas, United States

Texas Oncology-Denton South, Denton, Texas, United States

Texas Oncology-Fort Worth, Fort Worth, Texas, United States

Texas Oncology-Memorial City, Houston, Texas, United States

Texas Oncology-Lewisville, Lewisville, Texas, United States

Texas Oncology-Mesquite, Mesquite, Texas, United States

Texas Oncology-Midland Allison Cancer Center, Midland, Texas, United States

Texas Oncology, P.A. - Plano, Plano, Texas, United States

Cancer Care Centers of South Texas, San Antonio, Texas, United States

Texas Oncology - Sherman, Sherman, Texas, United States

Texas Oncology-Tyler, Tyler, Texas, United States

University of Virginia, Charlottesville, Virginia, United States

Virginia Oncology Associates, Norfolk, Virginia, United States

Oncology and Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care, Salem, Virginia, United States

Virginia Mason Medical Center, Seattle, Washington, United States

Seattle Cancer Care Alliance, Seattle, Washington, United States

Cancer Care Northwest, Spokane, Washington, United States

Yakima Valley Memorial Hospital/North Star Lodge, Yakima, Washington, United States

Cancer TEAM Bellin Health, Green Bay, Wisconsin, United States

Institut Jules Bordet, Bruxelles, , Belgium

GHdC - Site Notre Dame, Charleroi, , Belgium

Universtair Ziekenhuis Antwerpen, Edegem, , Belgium

UZ Gent Medische Oncologie, Gent, , Belgium

UZ Leuven, Campus Gasthuisberg, trialbureau Algemene Medische Oncologie, Leuven, , Belgium

Centre Hospitalier Universitaire de Liège- Site du Sart Tilman, Liège, , Belgium

Centre Hospitalier Universitaire Ambroise Paré, Mons,, , Belgium

GZA Ziekenhuizen, Campus St Augustinus, CLINICAL TRIALS ONCOLOGY, Wilrijk, , Belgium

British Columbia Cancer Agency, Vancouver, British Columbia, Canada

Odette Cancer Centre OCC Clinical Research, Toronto, Ontario, Canada

Princess Margaret Hospital, Toronto, Ontario, Canada

CHUM-Hopital Notre-Dame, Montreal, Quebec, Canada

MUHC- Montreal General Hospital, Montreal, Quebec, Canada

Hôpital Charles-LeMoyne - CICM, Québec, , Canada

Institut Bergonie Service Oncologie Médicale, Bordeaux, , France

Sorecoh, Le Mans, , France

Centre Oscar Lambret, Lille Cedex, , France

Institut Paoli Calmettes, Service Pharmacie, Marseille, , France

Centra Regional de Lutte contre le Cancer, Montpellier, , France

Institut Curie, UGEC, Paris, , France

Hopital Tenon Service oncologie médicale, Paris, , France

Centre Régional de Lutte Contre le Cancer Nantes Atlantique René Gauducheau, Saint Herblain, , France

Institut de Cancérologie Gustave Roussy, Villejuif, , France

Klinikum St. Marien Amberg, Amberg, , Germany

Onkoplus, Berlin, , Germany

Oncoresearch, Dortmund, , Germany

Universitaetsklinikum Erlangen, Erlangen, , Germany

Wilhelm-Anton-Hospital gGmbH, Goch, , Germany

Universitaetsklinikum Heidelberg, Heidelberg, , Germany

Universitaetsklinikum Ulm, Frauenklinik, Ulm, , Germany

Istituto tumori Giovanni Paolo II-ospedale oncologico, Oncologia Medica e Sperimentale, Bari, , Italy

Via Olgettina, Milano, , Italy

Azienda Ospedaliero Universitaria Pisana, U.O. Oncologia Medica, Pisa, , Italy

Oncologia Ospedale Infermi- Viale, Rimini, , Italy

Istituto Nazionale tumori Regina Elena IRCCS, Roma, , Italy

Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do, Korea, Republic of

Samsung Medical Center, Irwon-dong, Seoul, Korea, Republic of

Hematology-oncology Department, Ajou University Hospital, Sŏwŏn, Suwon, Korea, Republic of

Seoul National University Bundang Hospital, Gyeonggi-do, , Korea, Republic of

Hematology-oncology Department, Ewha Womans University Mokdong Hospital, Seoul, , Korea, Republic of

Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of

Asan Medical Center, Seoul, , Korea, Republic of

Seoul National University Hospital,, Soeul, , Korea, Republic of

VUmc, Amsterdam, , Netherlands

MUMC, Maastricht, , Netherlands

Tweesteden Ziekenhuis, Tilburg, , Netherlands

Leningrad Regional Oncology Dispensary, Kuz'molovskiy, , Russian Federation

State Institution "Russian Oncology Research Centre named after N.N. Blokhin RAMS", Moscow, , Russian Federation

Scientific Research Oncology Institute named after N.N. Petrov, Saint Petersburg, , Russian Federation

Non-state Health Institution "Dorozhnaya Clinical Hospital of OAO "Russian Railways", St. Petersburg, , Russian Federation

St. Petersburg State Budget Healthcare Institution "City Clinical Oncology Dispensary", St. Petersburg, , Russian Federation

Hospital Vall d'Hebron, Barcelona, , Spain

ICO l´Hospitalet - Hospital Duran i Reynals, Barcelona, , Spain

Hospital Universitari Arnau de Vilanova, Lleida, , Spain

Hospital General Universitario Gregorio Marañon, Madrid, , Spain

MD Anderson Cancer Center Arturo, Madrid, , Spain

Hospital Universitario Ramón y Cajal, Madrid, , Spain

Hospital Sant Joan de Reus, Tarragona, , Spain

Clinical Trials Unit, Velindre Cancer Centre, Cardiff, , United Kingdom

Beaston Oncology Center, Glasgow, , United Kingdom

St James University Hospital, Leeds, , United Kingdom

NCRN, London, , United Kingdom

The Christie Hospitals NHS Foundation Trust, Manchester, , United Kingdom

Nottingham City Hospital, Nottingham, , United Kingdom

Cancer Clinical Trials Centre, Weston Park Hospital, Sheffield, , United Kingdom

Contact Details

Name: Alison Hannah, MD

Affiliation: Nektar Therapeutics

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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