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Brief Title: Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-Small Cell Lung Cancer Who Have Progressed on Prior Anti- Programmed Death-ligand 1 (PD-[L]1) Therapy and Chemotherapy
Official Title: A Randomized, Open Label Phase 2/3 Study Comparing Cobolimab + Dostarlimab + Docetaxel To Dostarlimab + Docetaxel To Docetaxel Alone In Participants With Advanced Nonsmall Cell Lung Cancer Who Have Progressed On Prior Anti-PD-(L)1 Therapy And Chemotherapy (COSTAR Lung)
Study ID: NCT04655976
Brief Summary: This is a multi-center, parallel group treatment, Phase 2/3 open label study evaluating cobolimab in combination with dostarlimab and docetaxel in participants with advanced Non-small cell Lung Cancer (NSCLC) who have progressed on prior anti-PD-(L)1 therapy and chemotherapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
GSK Investigational Site, Cerritos, California, United States
GSK Investigational Site, Fountain Valley, California, United States
GSK Investigational Site, Los Angeles, California, United States
GSK Investigational Site, Oakland, California, United States
GSK Investigational Site, Roseville, California, United States
GSK Investigational Site, San Francisco, California, United States
GSK Investigational Site, San Francisco, California, United States
GSK Investigational Site, Santa Clara, California, United States
GSK Investigational Site, Vallejo, California, United States
GSK Investigational Site, Walnut Creek, California, United States
GSK Investigational Site, Norwich, Connecticut, United States
GSK Investigational Site, Washington, District of Columbia, United States
GSK Investigational Site, Orange City, Florida, United States
GSK Investigational Site, Honolulu, Hawaii, United States
GSK Investigational Site, Iowa City, Iowa, United States
GSK Investigational Site, Edgewood, Kentucky, United States
GSK Investigational Site, Louisville, Kentucky, United States
GSK Investigational Site, Billings, Montana, United States
GSK Investigational Site, Las Vegas, Nevada, United States
GSK Investigational Site, Bronx, New York, United States
GSK Investigational Site, Mineola, New York, United States
GSK Investigational Site, New York, New York, United States
GSK Investigational Site, New York, New York, United States
GSK Investigational Site, Northport, New York, United States
GSK Investigational Site, White Plains, New York, United States
GSK Investigational Site, Pittsburgh, Pennsylvania, United States
GSK Investigational Site, Pittsburgh, Pennsylvania, United States
GSK Investigational Site, Sioux Falls, South Dakota, United States
GSK Investigational Site, Knoxville, Tennessee, United States
GSK Investigational Site, Memphis, Tennessee, United States
GSK Investigational Site, Houston, Texas, United States
GSK Investigational Site, Fredericksburg, Virginia, United States
GSK Investigational Site, Tacoma, Washington, United States
GSK Investigational Site, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina
GSK Investigational Site, Florida, Buenos Aires, Argentina
GSK Investigational Site, Pergamino, Buenos Aires, Argentina
GSK Investigational Site, Cipoletti, Rio Negro, Río Negro, Argentina
GSK Investigational Site, Viedma, Río Negro, Argentina
GSK Investigational Site, Rosario, Santa Fe, Argentina
GSK Investigational Site, Ciudad Autónoma de Buenos Aires, , Argentina
GSK Investigational Site, La Rioja, , Argentina
GSK Investigational Site, Kurralta Park, South Australia, Australia
GSK Investigational Site, South Brisbane, South Australia, Australia
GSK Investigational Site, Hobart, Tasmania, Australia
GSK Investigational Site, Ballarat, Victoria, Australia
GSK Investigational Site, Melbourne, Victoria, Australia
GSK Investigational Site, Aalst, , Belgium
GSK Investigational Site, Hasselt, , Belgium
GSK Investigational Site, Kortrijk, , Belgium
GSK Investigational Site, Ondina, Bahia, Brazil
GSK Investigational Site, Fortaleza, Ceará, Brazil
GSK Investigational Site, Porto Alegre, Rio Grande Do Sul, Brazil
GSK Investigational Site, Blumenau, Santa Catarina, Brazil
GSK Investigational Site, Rio de Janeiro, , Brazil
GSK Investigational Site, Rio de Janeiro, , Brazil
GSK Investigational Site, São Paulo, , Brazil
GSK Investigational Site, Kingston, Ontario, Canada
GSK Investigational Site, Oshawa, Ontario, Canada
GSK Investigational Site, Sudbury, Ontario, Canada
GSK Investigational Site, Greenfield Park, Quebec, Canada
GSK Investigational Site, Montreal, Quebec, Canada
GSK Investigational Site, Helsinki, , Finland
GSK Investigational Site, Kuopio, , Finland
GSK Investigational Site, Tampere, , Finland
GSK Investigational Site, Turku, , Finland
GSK Investigational Site, Créteil Cedex, , France
GSK Investigational Site, Grenoble cedex 9, , France
GSK Investigational Site, Marseille, , France
GSK Investigational Site, Nice Cedex 2, , France
GSK Investigational Site, Quimper cedex, , France
GSK Investigational Site, Rennes Cedex 9, , France
GSK Investigational Site, Tours cedex 9, , France
GSK Investigational Site, Heidelberg, Baden-Wuerttemberg, Germany
GSK Investigational Site, Karlsruhe, Baden-Wuerttemberg, Germany
GSK Investigational Site, Augsburg, Bayern, Germany
GSK Investigational Site, Muenchen, Bayern, Germany
GSK Investigational Site, Muenchen, Bayern, Germany
GSK Investigational Site, Frankfurt am Main, Hessen, Germany
GSK Investigational Site, Frankfurt, Hessen, Germany
GSK Investigational Site, Oldenburg, Niedersachsen, Germany
GSK Investigational Site, Bonn, Nordrhein-Westfalen, Germany
GSK Investigational Site, Essen, Nordrhein-Westfalen, Germany
GSK Investigational Site, Koeln, Nordrhein-Westfalen, Germany
GSK Investigational Site, Halle, Sachsen-Anhalt, Germany
GSK Investigational Site, Dresden, Sachsen, Germany
GSK Investigational Site, Bad Berka, Thueringen, Germany
GSK Investigational Site, Berlin, , Germany
GSK Investigational Site, Athens, , Greece
GSK Investigational Site, Athens, , Greece
GSK Investigational Site, Athens, , Greece
GSK Investigational Site, Athens, , Greece
GSK Investigational Site, Larissa, , Greece
GSK Investigational Site, Patras, , Greece
GSK Investigational Site, Thessaloniki, , Greece
GSK Investigational Site, Thessaloniki, , Greece
GSK Investigational Site, Thessaloniki, , Greece
GSK Investigational Site, Avellino, Campania, Italy
GSK Investigational Site, Napoli, Campania, Italy
GSK Investigational Site, Milano, Lombardia, Italy
GSK Investigational Site, Milano, Lombardia, Italy
GSK Investigational Site, Monza, Lombardia, Italy
GSK Investigational Site, Torrette (AN), Marche, Italy
GSK Investigational Site, Orbassano (TO), Piemonte, Italy
GSK Investigational Site, Firenze, Toscana, Italy
GSK Investigational Site, Siena, Toscana, Italy
GSK Investigational Site, Perugia, Umbria, Italy
GSK Investigational Site, Kyoto, , Japan
GSK Investigational Site, Miyagi, , Japan
GSK Investigational Site, Osaka, , Japan
GSK Investigational Site, Yamaguchi, , Japan
GSK Investigational Site, Busan, , Korea, Republic of
GSK Investigational Site, Cheongju-si, Chungcheongbuk-do, , Korea, Republic of
GSK Investigational Site, Daegu-si, , Korea, Republic of
GSK Investigational Site, Gyeonggi-do, , Korea, Republic of
GSK Investigational Site, Seongnam-si, Gyeonggi-do, , Korea, Republic of
GSK Investigational Site, Seoul, , Korea, Republic of
GSK Investigational Site, Seoul, , Korea, Republic of
GSK Investigational Site, Seoul, , Korea, Republic of
GSK Investigational Site, Seoul, , Korea, Republic of
GSK Investigational Site, Suwon-Si, , Korea, Republic of
GSK Investigational Site, Benito Juarez, Ciudad De Mexico, Mexico
GSK Investigational Site, Mexico City, Ciudad De Mexico, Mexico
GSK Investigational Site, Mexico, Ciudad De Mexico, Mexico
GSK Investigational Site, Guadalajara, Jalisco, Mexico
GSK Investigational Site, Monterrey, Nuevo León, Mexico
GSK Investigational Site, Mexico City, , Mexico
GSK Investigational Site, Puebla, , Mexico
GSK Investigational Site, Amersfoort, , Netherlands
GSK Investigational Site, Enschede, , Netherlands
GSK Investigational Site, Groningen, , Netherlands
GSK Investigational Site, Harderwijk, , Netherlands
GSK Investigational Site, Nijmegen, , Netherlands
GSK Investigational Site, Utrecht, , Netherlands
GSK Investigational Site, Zwolle, , Netherlands
GSK Investigational Site, Bydgoszcz, , Poland
GSK Investigational Site, Gdynia, , Poland
GSK Investigational Site, Lodz, , Poland
GSK Investigational Site, Olsztyn, , Poland
GSK Investigational Site, Pila, , Poland
GSK Investigational Site, Poznan, , Poland
GSK Investigational Site, Bucuresti, , Romania
GSK Investigational Site, Craiova, , Romania
GSK Investigational Site, Craiova, , Romania
GSK Investigational Site, Otopeni, , Romania
GSK Investigational Site, Timisoara, , Romania
GSK Investigational Site, Chelyabinsk, , Russian Federation
GSK Investigational Site, Moscow, , Russian Federation
GSK Investigational Site, Pushkin, , Russian Federation
GSK Investigational Site, Saint-Petersburg, , Russian Federation
GSK Investigational Site, Badalona, , Spain
GSK Investigational Site, Barcelona, , Spain
GSK Investigational Site, Barcelona, , Spain
GSK Investigational Site, Burgos, , Spain
GSK Investigational Site, Cordoba, , Spain
GSK Investigational Site, La Coruña, , Spain
GSK Investigational Site, Las Palmas De Gran Canaria, , Spain
GSK Investigational Site, Madrid, , Spain
GSK Investigational Site, Madrid, , Spain
GSK Investigational Site, Madrid, , Spain
GSK Investigational Site, Madrid, , Spain
GSK Investigational Site, Madrid, , Spain
GSK Investigational Site, Majadahonda (Madrid), , Spain
GSK Investigational Site, Malaga, , Spain
GSK Investigational Site, Valencia, , Spain
GSK Investigational Site, Gävle, , Sweden
GSK Investigational Site, Solna, , Sweden
GSK Investigational Site, Uppsala, , Sweden
GSK Investigational Site, Hsinchu City, , Taiwan
GSK Investigational Site, New Taipei City, , Taiwan
GSK Investigational Site, Taichung, , Taiwan
GSK Investigational Site, Taipei City, , Taiwan
GSK Investigational Site, Bangkok, , Thailand
GSK Investigational Site, Dusit, , Thailand
GSK Investigational Site, Hat Yai, , Thailand
GSK Investigational Site, Khlong Luang, , Thailand
GSK Investigational Site, Muang, , Thailand
GSK Investigational Site, Adana, , Turkey
GSK Investigational Site, Antalya, , Turkey
GSK Investigational Site, Izmir, , Turkey
GSK Investigational Site, Edinburgh, , United Kingdom
GSK Investigational Site, London, , United Kingdom
GSK Investigational Site, London, , United Kingdom
GSK Investigational Site, Manchester, , United Kingdom
GSK Investigational Site, Whitchurch, Cardiff, , United Kingdom
Name: GSK Clinical Trials
Affiliation: GlaxoSmithKline
Role: STUDY_DIRECTOR