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Spots Global Cancer Trial Database for Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer

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Trial Identification

Brief Title: Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer

Official Title: A Phase I Open-Label, Dose-escalation Trial of Tumor Necrosis Factor Alpha and Interleukin-2 Coding Oncolytic Adenovirus (TILT-123) in Combination With Pembrolizumab in Patients With Immune Checkpoint Inhibitor Refractory Non-Small Cell Lung Cancer

Study ID: NCT06125197

Conditions

Lung Cancer

Interventions

TILT-123
KEYTRUDA®

Study Description

Brief Summary: This is an open label, Phase 1, dose escalation trial evaluating the safety of oncolytic adenovirus TILT-123 in combination with Pembrolizumab in patients with immune checkpoint inhibitor refractory non-small cell lung cancer.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Hoag Memorial Hospital Presbyterian, Newport Beach, California, United States

UCLA Jonsson Comprehensive Cancer Center, Santa Monica, California, United States

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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