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Brief Title: Prophylaxis of Venous Thromboembolism in Advanced Lung Cancer
Official Title: Phase Ⅲ Study of Prophylaxis of Venous Thromboembolism in Advanced Lung Cancer by Nadroparin
Study ID: NCT01980849
Brief Summary: To compare the efficacy and safety of prophylaxis of venous thromboembolism by Nadroparin during hospitalization to long-term usage in patients with advanced lung cancer treated by chemotherapy and/or radiotherapy.
Detailed Description: This is a prospective, multi-center, randomized and controlled study. Advanced lung cancer patients without venous thromboembolism(VTE) are included. The selected patients were randomized into A and B groups. Group A: Nadroparin given during hospitalization, 0.4mL, subcutaneously, qid; Group B: Nadroparin given by long-term, 0.4mL, subcutaneously, qid. The incidence of VTE , the risks of bleeding and overall survival in two groups of patients are studied at different time points.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The Department of Oncology,Southwest Hospital, Chongqing, Chongqing, China
The Department of Pulmonary and Critical Care Medicine,Southwest Hospital, Chongqing, Chongqing, China
The Department of Oncology,Ohtsubo Hospital, Chongqing, Chongqing, China
The Department of Oncology,Fuling Central Hospital, Chongqing, Chongqing, China
The Department of Oncology,Central Hospital, Xinxiang, Henan, China
The Department of Oncology,People's Hospital, Zhengzhou, Henan, China
The Department of Pulmonary and Critical Care Medicine,Cancer Hospital, Zhengzhou, Henan, China
The Department of Oncology,Henan University Affiliated Yihe Hospital, Zhengzhou, Henan, China
The Department of Oncology,Cancer Hospital, Baotou, Inner Mongolia, China
The Department of Oncology,Northern Hospital, Baotou, Inner Mongolia, China
The Department of Oncology,Inner Mongolia Autonomous Region Hospital, Hohhot, Inner Mongolia, China
The Department of Pulmonary and Critical Care Medicine,Medical University General Hospital cardiovascular and cerebrovascular disease hospital, Yinchuan, Ningxia, China
The Department of Pulmonary and Critical Care Medicine,Central Hospital, Baoji, Shaanxi, China
The Department of Pulmonary and Critical Care Medicine,Second People's Hospital, Xi'an, Shaanxi, China
The Department of Pulmonary and Critical Care Medicine, Second Affiliated Hospital of Jiaotong University, Xi'an, Shaanxi, China
The Department of Pulmonary and Critical Care Medicine, Tangdu Hospital, Xi'an, Shaanxi, China
The Department of Pulmonary and Critical Care Medicine, Xijing Hospital, Xi'an, Shaanxi, China
The Department of Oncology,First Affiliated Hospital of Jiaotong University, Xi'an, Shaanxi, China
The Department of Oncology,Yan'an University Hospital, Yan'an, Shaanxi, China
The Department of Oncology,Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
The Department of Lung oncology,Tumor Hospital, Chengdu, Sichuan, China
The Department of Oncology,People's Hospital, Chengdu, Sichuan, China
The Department of Oncology,First Affiliated Hospital of Medical University, Urumqi, Xinjiang, China
The Department of Pulmonary and Critical Care Medicine,First Affiliated Hospital of Medical University, Urumqi, Xinjiang, China