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Brief Title: A Phase 1/2 Study Evaluating ABT-751 in Combination With Alimta in Advanced Non-Small Cell Lung Cancer
Official Title: A Phase 1/2 Study Evaluating the Safety and Efficacy of ABT 751 in Combination With Pemetrexed Versus Pemetrexed Alone in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer
Study ID: NCT00297089
Brief Summary: To determine the efficacy of ABT-751 when administered in combination with standard pemetrexed in subjects with advanced or metastatic NSCLC. The Phase 1 portion of the study is complete and the study is currently enrolling subjects in Phase 2.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Site Reference ID/Investigator# 3358, Fayetteville, Arkansas, United States
Site Reference ID/Investigator# 4102, Hot Springs, Arkansas, United States
Site Reference ID/Investigator# 2127, Greenbrae, California, United States
Site Reference ID/Investigator# 2417, Fort Collins, Colorado, United States
Site Reference ID/Investigator# 5690, Torrington, Connecticut, United States
Site Reference ID/Investigator# 2411, Fort Lauderdale, Florida, United States
Site Reference ID/Investigator# 3363, Lakeland, Florida, United States
Site Reference ID/Investigator# 3352, Port St. Lucie, Florida, United States
Site Reference ID/Investigator# 3807, Atlanta, Georgia, United States
Site Reference ID/Investigator# 3353, Chicago, Illinois, United States
Site Reference ID/Investigator# 3359, Indianapolis, Indiana, United States
Site Reference ID/Investigator# 2416, Baltimore, Maryland, United States
Site Reference ID/Investigator# 2244, Baltimore, Maryland, United States
Site Reference ID/Investigator# 2401, Bethesda, Maryland, United States
Site Reference ID/Investigator# 3793, Peabody, Massachusetts, United States
Site Reference ID/Investigator# 3362, Worcester, Massachusetts, United States
Site Reference ID/Investigator# 2075, Kalamazoo, Michigan, United States
Site Reference ID/Investigator# 2418, Jefferson City, Missouri, United States
Site Reference ID/Investigator# 4170, St. Louis, Missouri, United States
Site Reference ID/Investigator# 3357, Lebanon, New Hampshire, United States
Site Reference ID/Investigator# 5098, Lake Success, New York, United States
Site Reference ID/Investigator# 2242, Huntersville, North Carolina, United States
Site Reference ID/Investigator# 2413, Columbus, Ohio, United States
Site Reference ID/Investigator# 3354, Bethelem, Pennsylvania, United States
Site Reference ID/Investigator# 6006, Philadelphia, Pennsylvania, United States
Site Reference ID/Investigator# 2414, Bristol, Tennessee, United States
Site Reference ID/Investigator# 2070, Tacoma, Washington, United States
Site Reference ID/Investigator# 4687, Brno, , Czech Republic
Site Reference ID/Investigator# 3337, Brno, , Czech Republic
Site Reference ID/Investigator# 4278, Kyjov, , Czech Republic
Site Reference ID/Investigator# 3328, Novy Jicin, , Czech Republic
Site Reference ID/Investigator# 3327, Olomouc, , Czech Republic
Site Reference ID/Investigator# 3343, Ostrava-Poruba, , Czech Republic
Site Reference ID/Investigator# 3344, Prague 2, , Czech Republic
Site Reference ID/Investigator# 3342, Prague 4, , Czech Republic
Site Reference ID/Investigator# 3411, Pribram, , Czech Republic
Site Reference ID/Investigator# 3405, Heraklion, , Greece
Site Reference ID/Investigator# 3403, Thessaloniki, , Greece
Site Reference ID/Investigator# 3406, Thessaloniki, , Greece
Site Reference ID/Investigator# 3331, Budapest, , Hungary
Site Reference ID/Investigator# 3333, Miskolc, , Hungary
Site Reference ID/Investigator# 3332, Szekesfehervar, , Hungary
Site Reference ID/Investigator# 3409, Amsterdam, , Netherlands
Site Reference ID/Investigator# 3319, Eindhoven, , Netherlands
Site Reference ID/Investigator# 3341, Haraderwijk, , Netherlands
Site Reference ID/Investigator# 3528, Hoorn, , Netherlands
Site Reference ID/Investigator# 3400, Bratislava, , Slovakia
Site Reference ID/Investigator# 3410, Martin, , Slovakia
Name: Gary Gordon, MD
Affiliation: AbbVie
Role: STUDY_DIRECTOR