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Spots Global Cancer Trial Database for CASCADE-LUNG: Cancer Screening Assay Using DELFI; A Clinical Validation Study in Lung

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Trial Identification

Brief Title: CASCADE-LUNG: Cancer Screening Assay Using DELFI; A Clinical Validation Study in Lung

Official Title: CASCADE-LUNG: Cancer Screening Assay Using DELFI; A Clinical Validation Study in Lung

Study ID: NCT05306288

Conditions

Lung Cancer

Study Description

Brief Summary: CASCADE-LUNG is an event-driven, multisite, prospective, observational, blood specimen collection study in the elevated-risk lung cancer screening population. The primary objective is to determine the sensitivity and specificity of the Delfi Lung Cancer ScreeningTest (DLCST).

Detailed Description: Participants will be enrolled into the DELFI-L201 study after informed consent and eligibility is confirmed. DELFI identifies circulating tumor DNA (ctDNA) to detect cancer. The study purpose is to validate the performance of the DELFI-based test for the detection of lung cancer among individuals eligible for routine lung cancer screening. Participants will have blood collected and medical record review at baseline and will have medical records reviews at two additional timepoints.

Eligibility

Minimum Age: 50 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Cullman Clinical Trials, Cullman, Alabama, United States

Science 37 (nationwide digital enrollment), Culver City, California, United States

Providence Facey Medical Foundation, Mission Hills, California, United States

Hoag Hospital, Newport Beach, California, United States

Paradigm Clinical Research Center, Inc., Redding, California, United States

San Francisco VA, San Francisco, California, United States

Clinical Research of California LLC, Walnut Creek, California, United States

SCL Health Research Institute, St. Mary's, Grand Junction, Colorado, United States

Paradigm Clinical Research Center, Wheat Ridge, Colorado, United States

Stamford Health, Stamford, Connecticut, United States

Advanced Research, Boynton Beach, Florida, United States

Morton Plant Hospital, Clearwater, Florida, United States

SIMEDHealth, LLC, Gainesville, Florida, United States

Galenus Group, Lehigh Acres, Florida, United States

Renstar Medical Research, Ocala, Florida, United States

Oviedo Medical Research, LLC, Oviedo, Florida, United States

United Medical Research, Port Orange, Florida, United States

Renew Health Clinical Research, Tampa, Florida, United States

American Clinical Trials, LLC., Acworth, Georgia, United States

Centricity Research Columbus Piedmont, Columbus, Georgia, United States

ClinCept, LLC, Columbus, Georgia, United States

Coastal Heritage Clinical Research, Hinesville, Georgia, United States

Centricity Research Gwinnett Pulmonology, Lawrenceville, Georgia, United States

Centricity Research Rincon Pulmonology, Rincon, Georgia, United States

OSF Saint Francis Medical Center, Peoria, Illinois, United States

Springfield Clinic, Springfield, Illinois, United States

St. Elizabeth Healthcare, Edgewood, Kentucky, United States

St. Clair Healthcare, Morehead, Kentucky, United States

Ochsner, New Orleans, Louisiana, United States

MaineHealth Cancer Care - Biddeford, Biddeford, Maine, United States

Johns Hopkins, Baltimore, Maryland, United States

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

Henry Ford Hospital, Detroit, Michigan, United States

Pulmonary Research Institute of Southeast Michigan, Farmington Hills, Michigan, United States

Minneapolis VA, Minneapolis, Minnesota, United States

Mayo Clinic, Rochester, Minnesota, United States

Hannibal Regional Healthcare System, Hannibal, Missouri, United States

Washington University, Saint Louis, Missouri, United States

Missouri Baptist Medical Center, Saint Louis, Missouri, United States

Somnos Clinical Research, Lincoln, Nebraska, United States

Internal Medicine Associate, Bridgeton, New Jersey, United States

CHRISTUS St. Vincent Regional Medical Center, Santa Fe, New Mexico, United States

Northwell Health, New Hyde Park, New York, United States

University of Rochester Medical Center, Rochester, New York, United States

SUNY Upstate Medical University, Syracuse, New York, United States

University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States

Duke University, Durham, North Carolina, United States

Durham VA, Durham, North Carolina, United States

East Carolina University, Greenville, North Carolina, United States

Coastal Carolina Health Care, P.A., New Bern, North Carolina, United States

University of Cincinnati Medical Center, Cincinnati, Ohio, United States

Cleveland Clinic, Cleveland, Ohio, United States

Hightower Clinical, Oklahoma City, Oklahoma, United States

Northwest Research Center, Portland, Oregon, United States

Oregon Health Sciences University, Portland, Oregon, United States

Clinical Research Associates of Central Pa, LLC, DuBois, Pennsylvania, United States

Lung Health Services, Lansdale, Pennsylvania, United States

University of Pennsylvania, Philadelphia, Pennsylvania, United States

Thomas Jefferson University, Philadelphia, Pennsylvania, United States

Pittsburgh VA Healthcare System, Pittsburgh, Pennsylvania, United States

Allegheny Health Network, Pittsburgh, Pennsylvania, United States

Ralph H Johnson VA, Charleston, South Carolina, United States

Medical University of South Carolina, Charleston, South Carolina, United States

LLM Research, Myrtle Beach, South Carolina, United States

Baptist Clinical Research Institute, Memphis, Tennessee, United States

Greater Heights Memorial Pulmonary and Sleep, Houston, Texas, United States

Houston Pulmonary Sleep and Allergy Associates, Houston, Texas, United States

North Houston Cancer Clinics, Huntsville, Texas, United States

CHRISTUS Trinity Clinic Pulmonary Medicine, Irving, Texas, United States

R&H Clinical Research, Inc., Katy, Texas, United States

Lumi Research, Kingwood, Texas, United States

Central Virginia VA Health System: Hunter Holmes McGuire, Richmond, Virginia, United States

UW Medicine Valley Medical Center, Renton, Washington, United States

Pan American Center for Oncology Trials, San Juan, , Puerto Rico

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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