⭐️⭐️⭐️⭐️⭐️ "A total no brainer"

⭐️⭐️⭐️⭐️⭐️ "Love this, so easy."

Spots is the easy way to track your skin, mole and cancer changes.

Spots Global Cancer Trial Database for Combination Chemotherapy and Exisulind in Treating Patients With Extensive-Stage Small Cell Lung Cancer

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Combination Chemotherapy and Exisulind in Treating Patients With Extensive-Stage Small Cell Lung Cancer

Official Title: A Phase II Study of Carboplatin, Etoposide, and Exisulind in Patients With Extensive Small Cell Lung Cancer

Study ID: NCT00041054

Conditions

Lung Cancer

Study Description

Brief Summary: RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Exisulind may make tumor cells more sensitive to chemotherapy. Combining chemotherapy with exisulind may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining chemotherapy with exisulind in treating patients who have extensive-stage small cell lung cancer.

Detailed Description: OBJECTIVES: * Determine the percentage of patients with extensive stage small cell lung cancer who live more than 12 months after treatment with carboplatin, etoposide, and exisulind. * Determine the response rate of patients treated with this regimen. * Determine the toxicity of this regimen in these patients. OUTLINE: This is a multicenter study. Patients receive carboplatin IV over 30 minutes on day 1 and etoposide IV over 30-60 minutes on days 1-3. Patients also receive oral exisulind twice daily on days 1-21. Treatment repeats every 21 days for up to 6 courses in the absence of disease progression or unacceptable toxicity. Patients are followed every 2 months for 1 year and then every 4 months for 2 years.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Northeast Alabama Regional Medical Center, Anniston, Alabama, United States

Rebecca and John Moores UCSD Cancer Center, La Jolla, California, United States

Cedars-Sinai Medical Center, Los Angeles, California, United States

Veterans Affairs Medical Center - San Diego, San Diego, California, United States

UCSF Comprehensive Cancer Center, San Francisco, California, United States

Veterans Affairs Medical Center - San Francisco, San Francisco, California, United States

CCOP - Christiana Care Health Services, Newark, Delaware, United States

Lombardi Cancer Center, Washington, District of Columbia, United States

Walter Reed Army Medical Center, Washington, District of Columbia, United States

Veterans Affairs Medical Center - Washington, DC, Washington, District of Columbia, United States

Broward General Medical Center, Fort Lauderdale, Florida, United States

Memorial Regional Hospital Comprehensive Cancer Center, Hollywood, Florida, United States

CCOP - Mount Sinai Medical Center, Miami Beach, Florida, United States

Florida Hospital Cancer Institute, Orlando, Florida, United States

Helen and Harry Gray Cancer Institute at Good Samaritan Medical Center, West Palm Beach, Florida, United States

MBCCOP - University of Illinois at Chicago, Chicago, Illinois, United States

Veterans Affairs Medical Center - Chicago (Westside Hospital), Chicago, Illinois, United States

University of Chicago Cancer Research Center, Chicago, Illinois, United States

Louis A. Weiss Memorial Hospital, Chicago, Illinois, United States

West Suburban Center for Cancer Care, River Forest, Illinois, United States

Saint Anthony Medical Center, Rockford, Illinois, United States

Fort Wayne Medical Oncology and Hematology, Incorporated, Fort Wayne, Indiana, United States

CCOP - Northern Indiana CR Consortium, South Bend, Indiana, United States

Hematology Oncology Associates of the Quad Cities, Bettendorf, Iowa, United States

Holden Comprehensive Cancer Center, Iowa City, Iowa, United States

Baptist Hospital East - Louisville, Louisville, Kentucky, United States

Marlene and Stewart Greenebaum Cancer Center, University of Maryland, Baltimore, Maryland, United States

Veterans Affairs Medical Center - Baltimore, Baltimore, Maryland, United States

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

University of Massachusetts Memorial Medical Center - University Campus, Worcester, Massachusetts, United States

Lakeland Medical Center - St. Joseph, Saint Joseph, Michigan, United States

Veterans Affairs Medical Center - Minneapolis, Minneapolis, Minnesota, United States

University of Minnesota Cancer Center, Minneapolis, Minnesota, United States

Veterans Affairs Medical Center - Columbia (Truman Memorial), Columbia, Missouri, United States

Ellis Fischel Cancer Center - Columbia, Columbia, Missouri, United States

Barnes-Jewish Hospital, Saint Louis, Missouri, United States

Siteman Cancer Center, Saint Louis, Missouri, United States

Missouri Baptist Cancer Center, Saint Louis, Missouri, United States

University of Nebraska Medical Center, Omaha, Nebraska, United States

CCOP - Southern Nevada Cancer Research Foundation, Las Vegas, Nevada, United States

Veterans Affairs Medical Center - Las Vegas, Las Vegas, Nevada, United States

Norris Cotton Cancer Center, Lebanon, New Hampshire, United States

Cooper University Hospital, Camden, New Jersey, United States

Veterans Affairs Medical Center - Buffalo, Buffalo, New York, United States

Roswell Park Cancer Institute, Buffalo, New York, United States

Elmhurst Hospital Center, Elmhurst, New York, United States

Queens Cancer Center of Queens Hospital, Jamaica, New York, United States

CCOP - North Shore University Hospital, Manhasset, New York, United States

North Shore University Hospital, Manhasset, New York, United States

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Weill Medical College of Cornell University, New York, New York, United States

Mount Sinai Medical Center, NY, New York, New York, United States

State University of New York - Upstate Medical University, Syracuse, New York, United States

Veterans Affairs Medical Center - Syracuse, Syracuse, New York, United States

CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C., Syracuse, New York, United States

Veterans Affairs Medical Center - Asheville, Asheville, North Carolina, United States

Lineberger Comprehensive Cancer Center, UNC, Chapel Hill, North Carolina, United States

NorthEast Oncology Associates, Concord, North Carolina, United States

Veterans Affairs Medical Center - Durham, Durham, North Carolina, United States

Duke Comprehensive Cancer Center, Durham, North Carolina, United States

Cape Fear Valley Health System, Fayetteville, North Carolina, United States

Lenoir Memorial Hospital Cancer Center, Kinston, North Carolina, United States

FirstHealth Moore Regional Hospital, Pinehurst, North Carolina, United States

New Hanover Regional Medical Center, Wilmington, North Carolina, United States

CCOP - Southeast Cancer Control Consortium, Winston-Salem, North Carolina, United States

Comprehensive Cancer Center at Wake Forest University, Winston-Salem, North Carolina, United States

Veterans Affairs Medical Center - Fargo, Fargo, North Dakota, United States

Arthur G. James Cancer Hospital - Ohio State University, Columbus, Ohio, United States

Western Pennsylvania Hospital, Pittsburgh, Pennsylvania, United States

Lifespan: The Miriam Hospital, Providence, Rhode Island, United States

Veterans Affairs Medical Center - Dallas, Dallas, Texas, United States

Simmons Cancer Center - Dallas, Dallas, Texas, United States

Green Mountain Oncology Group, Bennington, Vermont, United States

Vermont Cancer Center, Burlington, Vermont, United States

Veterans Affairs Medical Center - White River Junction, White River Junction, Vermont, United States

Martha Jefferson Hospital, Charlottesville, Virginia, United States

Virginia Oncology Associates - Norfolk, Norfolk, Virginia, United States

MBCCOP - Massey Cancer Center, Richmond, Virginia, United States

Oncology and Hematology Associates of Southwest Virginia, Inc., Roanoke, Virginia, United States

St. Mary's Medical Center, Huntington, West Virginia, United States

Ministry Medical Group - Northern Region, Rhinelander, Wisconsin, United States

McGill University, Montreal, Quebec, Canada

University of Puerto Rico School of Medicine Medical Sciences Campus, San Juan, , Puerto Rico

Contact Details

Name: Ramaswamy Govindan, MD

Affiliation: Washington University Siteman Cancer Center

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

Logo

Take Control of Your Skin and Body Changes Today.

Try out Spots for free, set up only takes 2 mins.

spots app storespots app store

Join others from around the world: