Spots Global Cancer Trial Database for Liquid Biopsy With PET/CT Versus PET/CT Alone in Diagnosis of Small Lung Nodules
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Trial Identification
Brief Title: Liquid Biopsy With PET/CT Versus PET/CT Alone in Diagnosis of Small Lung Nodules
Official Title: Liquid Biopsy in Combination With PET/CT Versus PET/CT Alone in Diagnosis of Small Lung Nodules
Study ID: NCT05066776
Interventions
Study Description
Brief Summary: The purpose of this study is to determine if a liquid biopsy, a method of detecting cancer from a blood draw, combined with a PET/CT scan, a type of radiological scan, is better at determining whether a lung nodule is cancerous when compared to a PET/CT scan alone. A PET/CT scan is already used for diagnosis of lung nodules, but its efficacy is uncertain in nodules 6-20 mm in size. Therefore, the PET/CT will be evaluated for its diagnostic ability in lesions this size alone and in combination with a liquid biopsy. Secondarily, a machine learning model will be created to see if the combination of the PET/CT imaging data and the liquid biopsy data can predict the presence of cancer.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
VA Palo Alto Health Care System, Palo Alto, California, United States
Contact Details
Name: Rajesh Shah, MD
Affiliation: VA Palo Alto Health Care System
Role: PRINCIPAL_INVESTIGATOR
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