Neoplasms

Respiratory Tract (Lung and Bronchial) Diseases

All Conditions

Lung Neoplasms

Respiratory Tract Neoplasms

Thoracic Neoplasms

Lung Diseases

Respiratory Tract Diseases

Serum samples were collected from patients with lung cancer at the time of their diagnosis, prior to the initiation of treatment. Diagnosis of lung adenocarcinoma was based on pathologic analysis.

Control subjects without known cancer and aged from 40 to 75 years should meet at least one of the following criteria: (1) current or ex-smoker with at least a 10 pack-year history, (2) a first-degree relative with a history of lung cancer, or (3) a clinical diagnosis of COPD.

Serum samples were collected from patients with lung cancer at the time of their diagnosis, prior to the initiation of treatment. Diagnosis of lung squamous cell carcinoma was based on pathologic analysis.

Serum samples from lung cancer patients were collected at the time of their diagnosis, prior to the initiation of treatment. Serum samples of control subjects were collected from a biobank

serum sample

Daniel Sessler, M.D.

This study aims to evaluate the performance of serum free fatty acids as biomarkers for the identification of lung cancer.

We will compare the concentration of free fatty acids and their metabolites between patients with lung cancer and control pulmonary patients without known cancer. The diagnostic accuracy will be assessed for potential predictors.

Blood will be sampled for FFA metabolites

Serum Free Fatty Acid Metabolite Biomarkers of Lung Cancer

Biochemical analysis of serum sample was conducted by an investigator who was strictly blinded to cancer status and patient characteristics.

The Cleveland Clinic

Serum samples were collected from patients with lung cancer at the time of their diagnosis, prior to the initiation of treatment. Diagnosis of lung adenocarcinoma was based on pathologic analysis.

serum sample: Serum samples from lung cancer patients were collected at the time of their diagnosis, prior to the initiation of treatment. Serum samples of control subjects were collected from a biobank

Lung Adenocarcinoma Patients

Control subjects without known cancer and aged from 40 to 75 years should meet at least one of the following criteria: (1) current or ex-smoker with at least a 10 pack-year history, (2) a first-degree relative with a history of lung cancer, or (3) a clinical diagnosis of COPD.

serum sample: Serum samples from lung cancer patients were collected at the time of their diagnosis, prior to the initiation of treatment. Serum samples of control subjects were collected from a biobank

Control Matched to Adenocarcinoma

Serum samples were collected from patients with lung cancer at the time of their diagnosis, prior to the initiation of treatment. Diagnosis of lung squamous cell carcinoma was based on pathologic analysis.

serum sample: Serum samples from lung cancer patients were collected at the time of their diagnosis, prior to the initiation of treatment. Serum samples of control subjects were collected from a biobank

Lung Squamous Cell Carcinoma Patients

Control Matched to Squamous Cell

Total

Age, Continuous

Sex: Female, Male

Never

Former

Current

Smoking status

Family history of lung cancer

COPD

Amount of Cigarette Smoking as Pack-year

Daniel Sessler, MD

Arachidonic Acid

Linoleic Acid

Hydroperoxyoctadecadienoyl phosphatidylcholine

Hydroxyoctadecadienoylphosphatidylcholine

Azelaoyl platelet activating factor

Azelaoyl phosphatidylcholine

C18-lysophospholipid platelet activating factor

C16-lyso-phosphatidylcholine

C16-lysophospholipid platelet activating factor

5-hydroxyeicosatetraenoic acid

11-hydroxyeicosatetraenoic acid

12-hydroxyeicosatetraenoic acid

15-hydroxyeicosatetraenoic acid

9-hydroxyoctadecadienoic acid

13-hydroxyoctadecadienoic acid

Compare Concentration of Fatty Acids and Their Metabolites

Overall Study

Spots Global Cancer Trial Database for Serum Free Fatty Acid Metabolite Biomarkers of Lung Cancer

Trial Identification

Conditions

Interventions

Study Description

Keywords

Eligibility

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