Spots Global Cancer Trial Database for Application of SERS Technology Based Intraoperative Navigation System in Lung Cancer

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Trial Identification

Brief Title: Application of SERS Technology Based Intraoperative Navigation System in Lung Cancer

Official Title: Application of Surface-enhanced Raman Scatting (SERS) Technology Based Intraoperative Navigation System in Lung Cancer

Study ID: NCT05881057

Conditions

Lung Cancer

Interventions

Study Description

Brief Summary: This study aims to explore the application of Surface-enhanced Raman Scatting (SERS) technology in lung cancer surgery and clarify its mechanism through multi-omics mass spectrometry platform, and then further prove the clinical transformation value of this technology.

Detailed Description: This study intends to apply the intraoperative navigation system based on Surface-enhanced Raman Scatting (SERS) technology to detect the PH of lung tissue, and to evaluate the benign and malignant resection margins of lung tissue based on this. In order to clarify the discrimination mechanism, a multi-omics mass spectrometry platform is planned to study the internal small molecules and pathway changes. In addition, the patients were followed up for five years to explore the correlation between the prognosis of patients and the PH of lung tissues and lymph nodes, which could prove the clinical transformation value of this technology.