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Brief Title: Early Stage Lung Cancer Screening With Low-dose Computed Tomographic
Official Title: Community-based Early Stage Lung Cancer Screening With Low-dose Computed Tomography in China
Study ID: NCT02898441
Brief Summary: The present study is a randomized controlled trial of LDCT screening for lung cancer versus usual care. 6000 high-risk subjects (age 45-70) were recruited and randomized to the Active arm (Baseline + 2 biennial repeated LDCT screening) or to the Passive arm, followed up in usual care (Baseline + 2 biennial repeated questionnaire inquiries). Follow-up for lung cancer incidence, lung cancer mortality and overall mortality was performed. Blood samples were stored from the Active arm in a Biobank. Management of positive screening test was carried out by a pre-specified protocol.
Detailed Description:
Minimum Age: 45 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Shanghai Chest hospital, Shanghai, Shanghai, China
Name: Baohui Han, MD, PhD
Affiliation: Shanghai Chest Hospital
Role: PRINCIPAL_INVESTIGATOR