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Brief Title: Analysis of Screen-detected Lung Cancers' Genomic Traits
Official Title: Analysis of Screen-detected Lung Cancers' Genomic Traits
Study ID: NCT04204499
Brief Summary: Prospective, observational cohort study of patients undergoing surgical resection for low dose CT (LDCT) screen-detected lung cancer (detected through the SUMMIT study- ClinicalTrials.gov Identifier: NCT03934866/ lung screening programmes), in which translational research is a fundamental aspect.
Detailed Description: The ASCENT study seeks to examine the genomic signatures of screen-detected cancers, in order to categorise the biological behaviour of such lesions and correlate this against non-invasive biological and radiological parameters. From these data, the plan is to explore strategies to characterise LDCT-detected cancers through non-invasive means, which the researchers believe may prove key in mitigating potential screening-associated harms.
Minimum Age: 50 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
St Bart's Hospital, London, , United Kingdom
UCLH, London, , United Kingdom
Name: Sam Janes
Affiliation: UCL
Role: PRINCIPAL_INVESTIGATOR