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Brief Title: Combination Paclitaxel, Carboplatin and Temozolomide
Official Title: Phase I Dose Finding Clinical Trial of Combination Paclitaxel, Carboplatin and Temozolomide for Subjects With Solid Tumor Malignancies.
Study ID: NCT00249964
Brief Summary: The purpose of this study is to determine the maximum tolerable dose of temozolomide in combination with fixed dose of paclitaxel and carboplatin and to determine the overall tumor response rate with this combination and to determine the duration of response.
Detailed Description: The objective of the research study is to test a combination of drugs to treat small cell lung cancer which has spread beyond the lungs (extensive cancer) or come back after earlier treatment (recurrent cancer).
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of New Mexico Cancer Center, Albuquerque, New Mexico, United States
Name: Fa-Chyi Lee, MD
Affiliation: University of New Mexico
Role: PRINCIPAL_INVESTIGATOR