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Spots Global Cancer Trial Database for Circulating Exosome RNA in Lung Metastases of Primary High-Grade Osteosarcoma

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Circulating Exosome RNA in Lung Metastases of Primary High-Grade Osteosarcoma

Official Title: A Pilot Study of Circulating Exosome RNA as Diagnostic and Prognostic Markers in Lung Metastases of Primary High-Grade Osteosarcoma

Study ID: NCT03108677

Interventions

Blood samples

Study Description

Brief Summary: The purpose of this study is to learn whether the profile of RNA from circulating exosomes can be used as a biomarker for lung metastases of primary high-grade osteosarcoma. Circulating exosomes plays roles in metastases in many kinds of cancer including osteosarcoma. By RNA profiling researchers may find lung metastases earlier than conventional work-up and predict the oncological outcomes.

Detailed Description: Investigators have performed a 4 patients pilot study under the oversight of hospital's ethics committee, and investigator found that the levels and mutations of circulating exosome RNA from patients with or without lung metastasis have significant differences. Then investigators wish to register this study to do a further research, in order to reveal the roles of circulating exosome RNA in metastases of osteosarcoma.

Eligibility

Minimum Age: 12 Years

Eligible Ages: CHILD, ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Ruijin Hospital Shanghai Jiao Tong University School of medicine, Shanghai, Shanghai, China

Contact Details

Name: Yuhui Shen, Ph.D., M.D.

Affiliation: Ruijin Hospital

Role: PRINCIPAL_INVESTIGATOR

Name: Weibin Zhang, Ph.D., M.D.

Affiliation: Ruijin Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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