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Brief Title: Radiofrequency Ablation in Resectable Colorectal Lung Metastasis
Official Title: Radiofrequency Ablation in Resectable Colorectal Lung Metastasis: A Phase-II Clinical Trial
Study ID: NCT00776399
Brief Summary: Lung metastasectomy is the only therapeutic option to provide a long-survival in patients with colorectal lung metastases. Recent studies have shown that radiofrequency (RF) ablation is a safe and useful therapeutic option for the treatment of unresectable lung metastases. In this phase-II trial, clinical utility of lung RF ablation will be evaluated in patients with resectable colorectal lung metastases.
Detailed Description: This will be a phase-II clinical trial. Lung metastasectomy is the only therapeutic option to provide a long-survival in patients with colorectal lung metastases. Recent studies have shown that radiofrequency (RF) ablation is a safe and useful therapeutic option for the treatment of unresectable lung metastases. In this clinical trial, clinical utility of lung RF ablation will be evaluated. Patients with resectable lung metastases will receive lung RF ablation. All subjects will be followed for overall survival, safety, change in respiratory function, cancer-specific survival, and local tumor progression.
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Anjo kosei hospital, Anjo, Aichi, Japan
Aichi Cancer Center, Nagoya, Aichi, Japan
Hokkaido University, Sapporo, Hokkaidou, Japan
Yamada red-cross hospital, Ise, Mie, Japan
Matsusaka munipal hospital, Matsusaka, Mie, Japan
Matsusaka central hospital, Matsusaka, Mie, Japan
Suzuka Kaisei Hospital, Suzuka, Mie, Japan
Suzuka central hospital, Suzuka, Mie, Japan
Toyama hospital, Tsu, Mie, Japan
Mie central medical center, Tsu, Mie, Japan
Mie University, Tsu, Mie, Japan
Mie prefectual medical center, Yokkaichi, Mie, Japan
Okayama University, Kayama, Okayama, Japan
Kumamoto University, Kumamoto, , Japan
Kyoto Prefectual University of Kyoto, Kyoto, , Japan
Okayama Saiseikai Hospital, Okayama, , Japan
Name: Haruyuki Takaki, MD
Affiliation: Department of Radiology, Mie University School of Medicine
Role: STUDY_DIRECTOR