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Brief Title: Anti-MUC1 CAR T Cells and PD-1 Knockout Engineered T Cells for NSCLC
Official Title: A Clinical Study of Anti-MUC1 CAR T Cells and PD-1 Knockout Engineered T Cells for Patients With Advanced Non-small Cell Lung Cancer
Study ID: NCT03525782
Brief Summary: The study is to assess the safety and efficacy of the anti-MUC1 CAR T cells and /or PD-1 knockout engineered T cells for patients with advanced non-small cell lung cancer.
Detailed Description: This is a combined phase 1 and 2 clinical study. The study is to assess the safety and efficacy of the anti-MUC1 CAR T cells and /or PD-1 knockout engineered T cells for patients with advanced non-small cell lung cancer. The treatment outcomes will be compared.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, Guangdong, China
Professor Size Chen, Guangzhou, Guangdong, China
Professor Size Chen, Guangzhou, Guangdong, China