Spots Global Cancer Trial Database for LUX-Lung 7: A Phase IIb Trial of Afatinib(BIBW2992) Versus Gefitinib for the Treatment of 1st Line EGFR Mutation Positive Adenocarcinoma of the Lung
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Trial Identification
Brief Title: LUX-Lung 7: A Phase IIb Trial of Afatinib(BIBW2992) Versus Gefitinib for the Treatment of 1st Line EGFR Mutation Positive Adenocarcinoma of the Lung
Official Title: LUX-Lung 7: A Randomised, Open-label Phase IIb Trial of Afatinib Versus Gefitinib as First-line Treatment of Patients With EGFR Mutation Positive Advanced Adenocarcinoma of the Lung
Study ID: NCT01466660
Conditions
Study Description
Brief Summary: This is a randomised, open-label, phase IIb trial of afatinib to compare to gefitinib in first-line treatment setting with patients who are having epidermal growth factor receptor mutation positive advanced adenocarcinoma of the lung.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Chris Obrien Lifehouse, Camperdown, New South Wales, Australia
St George Hospital, Kogarah, New South Wales, Australia
The Prince Charles Hospital, Chermside, Queensland, Australia
Haematology & Oncology Clinics of Australasia (HOCA), South Brisbane, Queensland, Australia
Box Hill Hospital, Box Hill, Victoria, Australia
Austin Health, Heidelberg, Victoria, Australia
Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
Cross Cancer Institute (University of Alberta), Edmonton, Alberta, Canada
British Columbia Cancer Agency (BCCA) - Fraser Valley Cancer, Surrey, British Columbia, Canada
BC Cancer Agency - Vancouver, Vancouver, British Columbia, Canada
Lakeridge Health Oshawa, Oshawa, Ontario, Canada
The Ottawa Hospital, Ottawa, Ontario, Canada
Montreal General Hospital - McGill University Health Centre, Montreal, Quebec, Canada
Cancer Hospital of Chinese Academy of Medical Science, Beijing, , China
Beijing Cancer Hospital, Beijing, , China
Sun Yat-Sen University Cancer Center, Guangzhou, , China
The Affiliated Cancer Hospital, Guangxi Medical University, Nan Ning, , China
Shanghai Chest Hospital, Shanghai, , China
Zhongshan Hospital Fudan University, Shanghai, , China
The First Hospital of Chinese Medical University, Shenyang, , China
CTR Oncologie du Pays Basque, Onco, Bayonne, Bayonne, , France
CTR François Baclesse, Caen, , France
HOP Intercommunal, Créteil, , France
HOP Michallon, La Tronche, , France
HOP Dupuytren 1, Limoges Cedex, , France
CTR Leon Berard, Lyon, , France
CTR René Gauducheau, Saint Herblain, , France
HOP Sud-Réunion, Pneumo, Saint Pierre, St-Pierre - La Réunion, , France
Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH, Essen, , Germany
Klinikum Esslingen GmbH, Esslingen, , Germany
Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Mainz, , Germany
Queen Mary Hospital, Hongkong, , Hong Kong
Prince of Wales Hospital, Shatin, , Hong Kong
Beaumont Hospital, Dublin 9, , Ireland
St James's Hospital, Dublin, , Ireland
Chungbuk National University Hospital, Cheongju, , Korea, Republic of
Gachon University Gil Medical Center, Incheon, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Oslo Universitetssykehus HF, Radiumhospitalet, Oslo, , Norway
National Cancer Centre, Singapore, , Singapore
Johns Hopkins Singapore International Medical Center, Singapore, , Singapore
Hospital Universitario 12 de Octubre, Madrid, , Spain
Hospital Regional Universitario de Málaga, Malaga, , Spain
Hospital Central de Asturias, Oviedo, , Spain
Hospital Universitario Marqués de Valdecilla, Santander, , Spain
Hospital Virgen del Rocío, Sevilla, , Spain
Sahlgrenska US, Göteborg, Göteborg, , Sweden
Universitetssjukhuset, Linköping, Linköping, , Sweden
Skånes universitetssjukhus, Lund, Lund, , Sweden
Karolinska Univ. sjukhuset, Stockholm, , Sweden
Taichung Veterans General Hospital, Taichung, , Taiwan
NCKUH, Tainan, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
Taipe Veterans General Hospital, Taipei, , Taiwan
Chang Gung Memorial Hospital(Linkou), Tao-Yuan, , Taiwan
Aberdeen Royal Infirmary, Aberdeen, , United Kingdom
Birmingham City Hospital, Birmingham, , United Kingdom
Velindre Cancer Centre, Cardiff, , United Kingdom
Western General Hospital, Edinburgh, , United Kingdom
Royal Surrey County Hospital, Guildford, , United Kingdom
Contact Details
Name: Boehringer Ingelheim
Affiliation: Boehringer Ingelheim
Role: STUDY_CHAIR
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