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Brief Title: Sputum Cytometry Analysis in Lung Cancer Screening After Professional Asbestos Exposure
Official Title: Interest of Morphometric Analysis of Sputum Cytology for Lung Cancer Screening in Workers Highly Exposed to Asbestos - Exploratory Analysis of Biomarkers Predictive for Lung Cancer
Study ID: NCT01687647
Brief Summary: Workers exposed to asbestos are at high risk of lung cancer. Medical follow-up of this population relies on repeated CT-scans which are more accurate for detection of peripheral lesions, and expose to X-rays and to risk of false-positives. Analysis of sputum using automate cytometry may be of interest in this population, alone or in combination with CT-scan. An ancillary study will evaluate the interest of blood predictive biomarkers.
Detailed Description:
Minimum Age: 56 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Caen University Hospital, Caen, , France
Le Havre Hospital, Le Havre, , France
Rouen University Hospital, Rouen, , France
Name: Lydia GUITTET, MD,PhD
Affiliation: Caen University Hospital, INSERM
Role: STUDY_DIRECTOR