Spots Global Cancer Trial Database for Pulmonary Rehabilitation in Lymphangioleiomyomatosis
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Trial Identification
Brief Title: Pulmonary Rehabilitation in Lymphangioleiomyomatosis
Official Title: Evaluation of the Impact of a Pulmonary Rehabilitation Program on Exercise Capacity in Patients With Lymphangioleiomyomatosis
Study ID: NCT02009241
Conditions
Interventions
Study Description
Brief Summary: Lymphangioleiomyomatosis (LAM) is a rare disease in which reduced exercise capacity is frequently present. The mechanisms applied are airflow obstruction, abnormal diffusion capacity and dynamic hyperinflation (DH). Pulmonary rehabilitation (PR) has proved benefit in improving exercise tolerance, dyspnea, and quality of life in chronic obstructive pulmonary disease. There are no studies evaluating the impact of PR in patients with LAM. The hypothesis under study is that PR determine improvement in exercise capacity, dyspnea, quality of life, muscle force, functional limitation and DH in these patients.
Detailed Description:
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Pulmonary Division, Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo, SP, Brazil
Contact Details
Name: Mariana S Araujo, MD
Affiliation: Pulmonary Division, Heart Institute (InCor), University of Sao Paulo Medical School
Role: PRINCIPAL_INVESTIGATOR
Name: Carlos RR Carvalho, PhD
Affiliation: Pulmonary Division, Heart Institute (InCor), University of Sao Paulo Medical School
Role: PRINCIPAL_INVESTIGATOR
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