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Brief Title: Tumor Infiltrating Lymphocyte Therapy for Pediatric High Risk Solid Tumors
Official Title: Tumor Infiltrating Lymphocytes in Pediatric Malignant Solid Tumors: A Prospective Biobanking Study and Phase I Clinical Trial
Study ID: NCT06047977
Brief Summary: Part One of this study will determine the feasibility of creating Tumor-Infiltrating Lymphocyte (TIL) product prospectively from high-risk pediatric solid tumors. Part Two of this study will determine the safety of TIL therapy with lymphodepleting chemotherapy and post-TIL Interleukin-2 in high-risk pediatric solid tumors
Detailed Description:
Minimum Age: 1 Year
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Johns Hopkins All Children's Hospital, Saint Petersburg, Florida, United States
Johns Hopkins All Children's Hospital, Saint Petersburg, Florida, United States
Name: Jonathan Metts, MD
Affiliation: Johns Hopkins All Children's Hospital
Role: PRINCIPAL_INVESTIGATOR