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Brief Title: A Phase 1b Study Evaluating GS-9820 in Subjects With Lymphoid Malignancies
Official Title: A Phase 1b Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of GS-9820 in Subjects With Lymphoid Malignancies
Study ID: NCT01705847
Brief Summary: This study is to determine the appropriate dosing regimen of GS-9820 in subjects with lymphoid malignancies. This is a Phase 1b, open-label, dose-escalation and expansion study evaluating the safety, pharmacokinetics, pharmacodynamics, and antitumor activity of GS-9820.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
VU Medical Center (VUmc), Amsterdam, , Netherlands
Academic Medical Center, Amsterdam, , Netherlands
St. Antonius Hospital, Nieuwegein, , Netherlands
Erasmus MC - Daniel den Hoed Cancer Center, Rotterdam, , Netherlands
Name: Henry Adewoye, MD
Affiliation: Gilead Sciences
Role: STUDY_DIRECTOR