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Brief Title: Omic Technologies Applied to the Study of B-cell Lymphoma for the Discovery of Diagnostic and Prognosis Biomarkers
Official Title: Omic Technologies Applied to the Study of Diffuse Large B-cell Lymphoma and High-grade B-cell Lymphoma for the Discovery of Diagnostic and Prognosis Biomarkers
Study ID: NCT05834426
Brief Summary: The goal of this observational study is to determine the plasma metabolomic profile in diffuse large B-cell lymphoma and high-grade B lymphomas patients before, during and after treatment by ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry (UPLC-QTOFMS)
Detailed Description: The main question it aims to answer is the correlation between the plasma metabolomic profile of diffuse large B-cell lymphoma and high-grade B lymphomas patients before and after treatment determined by ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry (UPLC-QTOFMS) and analysed with MetaboAnalyst web platform to identify specific over- or under-expressed markers.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Instituto Oncológico Nacional Dr. Juan Tanca Marengo, Guayaquil, Guayas, Ecuador
Name: Katherine García Matamoros, MD
Affiliation: Sociedad de Lucha Contra el Cáncer del Ecuador
Role: PRINCIPAL_INVESTIGATOR
Name: Fernanda Bertuccez Cordeiro, PhD
Affiliation: Escuela Superior Politécnica del Litoral
Role: PRINCIPAL_INVESTIGATOR