Spots Global Cancer Trial Database for A Study of ONTAK in Patients With Relapsed or Refractory, B-Cell Non Hodgkin's Lymphoma
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Trial Identification
Brief Title: A Study of ONTAK in Patients With Relapsed or Refractory, B-Cell Non Hodgkin's Lymphoma
Official Title: A Phase II Multicenter Study of ONTAK in Patients With Relapsed or Refractory, B-Cell Non-Hodgkins Lymphoma.
Study ID: NCT00211276
Conditions
Interventions
Study Description
Brief Summary: The goal of this clinical research study is to find out if the study drug, ONTAK (denileukin diftitox), can shrink or slow the growth of B-cell non-Hodgkin's lymphoma (NHL) in patients whose disease has not responded to prior treatments, or has relapsed after an initial response to prior treatments. The safety of treatment with ONTAK will also be studied. The hypothesis is that patients with relapsed or refractory B-cell NHL and mild to moderate myelosuppression treated with ONTAK at a new dosing regimen will respond sufficiently to warrant further study.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Tower Cancer Research Foundation, Beverly Hills, California, United States
Pacific Coast Hematology/Oncology, Fountain Valley, California, United States
University of California, Los Angeles, Los Angeles, California, United States
Emory University, Atlanta, Georgia, United States
Rush University Medical Center, Chicago, Illinois, United States
Siouxland Hematology-Oncology, Sioux City, Iowa, United States
Washington University Siteman Cancer Center, St. Louis, Missouri, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Roswell Park Cancer Institute, Buffalo, New York, United States
St. Vincent's Comprehensive Cancer Center, New York, New York, United States
Case Comprehensive Cancer Center, Cleveland, Ohio, United States
The Western Pennsylvania Hospital, Pittsburgh, Pennsylvania, United States
Contact Details
Name: Myron Czuczman, MD
Affiliation: Roswell Park Cancer Institute
Role: PRINCIPAL_INVESTIGATOR
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