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Spots Global Cancer Trial Database for A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma

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Trial Identification

Brief Title: A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma

Official Title: A Phase 2 Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL)

Study ID: NCT01421667

Study Description

Brief Summary: This is an open-label, multicenter, phase 2 clinical trial to evaluate the efficacy and safety of brentuximab vedotin as a single agent in patients with CD30-positive non-Hodgkin lymphoma (NHL) (Part A). The study will also evaluate the safety and efficacy of brentuximab vedotin in combination with rituximab in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) (Part B) as well as further evaluate correlation of CD30 expression and response in DLBCL (Part C).

Detailed Description:

Eligibility

Minimum Age: 6 Years

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Alabama at Birmingham, Birmingham, Alabama, United States

City of Hope, Duarte, California, United States

PMK Medical Group Inc., DBA Ventura County Hematology Oncology Specialists, Oxnard, California, United States

Stanford Cancer Center, Stanford, California, United States

Rocky Mountain Cancer Centers - Aurora, Aurora, Colorado, United States

Colorado Blood Cancer Institute, Denver, Colorado, United States

Cancer Specialists of North Florida - St. Augustine, St. Augustine, Florida, United States

Emory Winship Cancer Institute, Atlanta, Georgia, United States

Northwestern University, Chicago, Illinois, United States

University of Chicago, Chicago, Illinois, United States

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Minnesota Oncology Hematology P.A., Minneapolis, Minnesota, United States

Washington University School of Medicine, St. Louis, Missouri, United States

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States

Hackensack University Medical Center, Hackensack, New Jersey, United States

New York Oncology Hematology, P.C., Albany, New York, United States

NYU Clinical Cancer Center, New York, New York, United States

Columbia University Medical Center, New York, New York, United States

Memorial Sloan Kettering Cancer Center, New York, New York, United States

Cleveland Clinic, The, Cleveland, Ohio, United States

Willamette Valley Cancer and Research / USOR, Eugene, Oregon, United States

Medical University of South Carolina, Charleston, South Carolina, United States

St. Francis Hospital, Greenville, South Carolina, United States

Texas Oncology - Medical City Dallas, Dallas, Texas, United States

Charles A. Sammons Cancer Center, Dallas, Texas, United States

Texas Oncology-Southwest Fort Worth, Fort Worth, Texas, United States

MD Anderson Cancer Center / University of Texas, Houston, Texas, United States

Texas Oncology - Seton Williamson, Round Rock, Texas, United States

Texas Oncology - Tyler, Tyler, Texas, United States

Virginia Cancer Specialists, PC, Fairfax, Virginia, United States

Swedish Cancer Institute Medical Oncology, Edmonds, Washington, United States

Seattle Cancer Care Alliance / University of Washington Medical Center, Seattle, Washington, United States

Northwest Cancer Specialists, P.C., Vancouver, Washington, United States

British Columbia Cancer Agency - Vancouver Centre, Vancouver, British Columbia, Canada

Contact Details

Name: Corinna Palanca-Wessels, MD, PhD

Affiliation: Seagen Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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