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Brief Title: FT819 in Subjects With B-cell Malignancies
Official Title: A Phase I Study of FT819 in Subjects With B-cell Malignancies
Study ID: NCT04629729
Brief Summary: This is a Phase I dose-finding study of FT819 as monotherapy and in combination with IL-2 in subjects with relapsed/refractory B-cell Lymphoma, Chronic Lymphocytic Leukemia and Precursor B-cell Acute Lymphoblastic Leukemia. The study will consist of a dose-escalation stage and an expansion stage where participants will be enrolled into indication-specific cohorts.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Alabama at Birmingham, Birmingham, Alabama, United States
Mayo Arizona, Phoenix, Arizona, United States
UC Davis, Davis, California, United States
UCLA Ronald Reagan Medical Center, Los Angeles, California, United States
Stanford Cancer Institute, Palo Alto, California, United States
Mayo Florida, Jacksonville, Florida, United States
University of Iowa, Iowa City, Iowa, United States
Norton Cancer Institute, St. Matthews Campus, Louisville, Kentucky, United States
Mayo Minnesota, Rochester, Minnesota, United States
University of Nebraska Medical Center, Omaha, Nebraska, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Oregon Health & Sciences University, Portland, Oregon, United States
MD Anderson Cancer Center, Houston, Texas, United States
University of Wisconsin-Madison, Madison, Wisconsin, United States
Name: Fate Trial Disclosure
Affiliation: Fate Therapeutics
Role: STUDY_DIRECTOR