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Brief Title: Trial to Define the Safety and Tolerability of SGN-40, Rituximab, and Gemcitabine in Patients With DLBCL
Official Title: A Phase Ib Study of SGN-40 in Combination With Rituximab and Gemcitabine for the Treatment of Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Study ID: NCT00655837
Brief Summary: The purpose of this study is to determine safety and tolerability of combination therapy of SGN-40 with gemcitabine and rituximab for the treatment of lymphoma. This study is also intended to estimate how well your disease responds to this treatment.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Alabama at Birmingham, Birmingham, Alabama, United States
Mayo Clinic Arizona, Scottsdale, Arizona, United States
University of Colorado, Aurora, Colorado, United States
Oncology Specialists, Park Ridge, Illinois, United States
Washington University School of Medicine, St. Louis, Missouri, United States
Nevada Cancer Institute, Las Vegas, Nevada, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Duke University Medical Center, Durham, North Carolina, United States
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Name: Nancy Whiting, PharmD
Affiliation: Seagen Inc.
Role: STUDY_DIRECTOR