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Brief Title: Study of SGN-40 in Patients With Relapsed Diffuse Large B-Cell Lymphoma
Official Title: A Phase II Study of SGN-40 (Anti-huCD40 mAb) in Patients With Relapsed Diffuse Large B-Cell Lymphoma (DLBCL)
Study ID: NCT00435916
Brief Summary: This is a Phase II, open-label, multidose trial of SGN-40 designed to estimate objective response rate and assess toxicity in patients with relapsed DLBCL.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Alabama at Birmingham, Birmingham, Alabama, United States
Mayo Clinic-Arizona, Scottsdale, Arizona, United States
University of California Los Angeles, Los Angeles, California, United States
Stanford University Medical Center, Palo Alto, California, United States
Sharp Healthcare, San Diego, California, United States
Georgetown University, Washington, District of Columbia, United States
Northwestern University, Chicago, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
Mayo Clinic-Rochester, Rochester, Minnesota, United States
Washington University School of Medicine, St. Louis, Missouri, United States
Weill Medical College of Cornell University, New York, New York, United States
Charleston Hematology Oncology Associates, PA, Charleston, South Carolina, United States
Swedish Cancer Institute, Seattle, Washington, United States
University of Wisconsin, Madison, Wisconsin, United States
Name: Nancy Whiting, PharmD
Affiliation: Seagen Inc.
Role: STUDY_DIRECTOR