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Brief Title: Evaluation of Bay 59-8862 in Patients With Aggressive, Refractory Non-Hodgkin's Lymphoma
Official Title: An Open Phase II, Multi Center Trial of BAY 59-8862 in Patients With Aggressive, Refractory Non-Hodgkin's Lymphoma
Study ID: NCT00044551
Brief Summary: Almost two-thirds of lymphoma cases are Non-Hodgkin's Lymphomas (NHL). NHL is a malignant process that affects lymphoid cells found both in the lymph nodes and extranodally. Incidence and mortality rates from NHL are highest in developed countries. While many patients with aggressive NHL are curable with initial anthracycline-containing regimens, the majority of patients will relapse or prove refractory to initial therapy. The prognosis of patients with disease recurrence following a multidrug regimen is also limited. The current protocol is designed to test the safety and efficacy of BAY 59-8862 in patients with Aggressive Refractory Non-Hodgkin's Lymphoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Miami Beach, Florida, United States
, Chicago, Illinois, United States
, Shreveport, Louisiana, United States
, New Brunswick, New Jersey, United States
, Bronx, New York, United States
, Brooklyn, New York, United States
, Manhasset, New York, United States
, Syracuse, New York, United States
, Valhalla, New York, United States
, Cleveland, Ohio, United States
, Memphis, Tennessee, United States
, Seattle, Washington, United States
, Milwaukee, Wisconsin, United States
, Edmonton, Alberta, Canada
, Paris, , France
, Pierre Benite, , France
, Vandoeuvre-les-nancy, , France
, Freiburg, Baden-Württemberg, Germany
, Berlin, , Germany
, Amsterdam, , Netherlands
, Groene Hilledijk, , Netherlands
, Cambridge, Cambridgeshire, United Kingdom
, Maidstone, Kent, United Kingdom
Name: Bayer Study Director
Affiliation: Bayer
Role: STUDY_DIRECTOR