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Brief Title: A Study of ONTAK and CHOP in Newly Diagnosed, Peripheral T-Cell Lymphoma
Official Title: A Pilot Phase II Study to Determine the Safety and Efficacy of the Combination of ONTAK With CHOP in Peripheral T-Cell Lymphoma.
Study ID: NCT00211185
Brief Summary: Study of ONTAK and CHOP (chemotherapy drugs) to find out their ability to make Peripheral T-cell lymphoma disappear (for any period of time) and potentially lengthen life. The study will also compare what kind of side effects these drugs cause and how often they occur. The hypothesis is that patients with newly diagnosed peripheral T-Cell lymphoma, when given ONTAK + CHOP, will tolerate the treatment and will have a 20% improvement in response rate when compared to CHOP alone.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Birmingham Hematology and Oncology, Birmingham, Alabama, United States
Hematology Oncology Associates, Phoenix, Arizona, United States
Stanford Cancer Center, Stanford, California, United States
Rocky Mountain Cancer Center, Denver, Colorado, United States
Yale University School of Medicine, New Haven, Connecticut, United States
Ocala Oncology Center, Ocala, Florida, United States
Cancer Centers of Florida, P.A., Ocoee, Florida, United States
Hematology Oncology Associates of IL, Chicago, Illinois, United States
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
Cancer Care & Hematology Specialists of Chicagoland, Niles, Illinois, United States
Siouxland Hematology Oncology, Sioux City, Iowa, United States
Kansas City Cancer Centers, Lenexa, Kansas, United States
Dana Farber/ Harvard Cancer Center, Boston, Massachusetts, United States
New England Medical Center, Boston, Massachusetts, United States
Minnesota Oncology Hematology, P.A., Minneapolis, Minnesota, United States
Missouri Cancer Associates, Columbia, Missouri, United States
Kansas City Cancer Centers, Kansas City, Missouri, United States
St. Joseph Oncology Inc., Saint Joseph, Missouri, United States
Arch Medical Services, Saint Louis, Missouri, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Hematology Oncology Associates of NNJ, Morristown, New Jersey, United States
New Mexico Cancer Care Associates, Santa Fe, New Mexico, United States
New York Oncology Hematology, P.C., Albany, New York, United States
Raleigh Hematology Oncology Associates, Cary, North Carolina, United States
Barrett Cancer Center-University of Cincinnati, Cincinnati, Ohio, United States
Greater Dayton Cancer Center, Kettering, Ohio, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
Cancer Centers of the Carolinas, Greenville, South Carolina, United States
Texas Cancer Center, Arlington, Texas, United States
Marnie McFaddin Ward Cancer Center, Beaumont, Texas, United States
Texas Oncology,P.A., Bedford, Texas, United States
Texas Cancer Center at Medical City, Dallas, Texas, United States
The Texas Cancer Center, Dallas, Texas, United States
El Paso Cancer Treatment Center, El Paso, Texas, United States
Texas Oncology, Fort Worth, Texas, United States
Texas Oncology, Garland, Texas, United States
Longview Cancer Center, Longview, Texas, United States
Allison Cancer Center, Midland, Texas, United States
West Texas Cancer Center, Odessa, Texas, United States
HOAST Medical Dr., San Antonio, Texas, United States
Tyler Cancer Center, Tyler, Texas, United States
Waco Cancer Care and Research Center, Waco, Texas, United States
Virginia Oncology Associates, Norfolk, Virginia, United States
Oncology and Hematology Associates of SW VA Inc., Salem, Virginia, United States
Puget Sound Cancer Center, Edmonds, Washington, United States
Cancer Care Northwest, Spokane, Washington, United States
Northwest Cancer Specialists, Vancouver, Washington, United States
Yakima Valley Memorial Hospital/North Star Lodge, Yakima, Washington, United States