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Spots Global Cancer Trial Database for A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)

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Trial Identification

Brief Title: A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)

Official Title: A Phase 2, Open-label, Single-arm, Two-cohort Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) or Relapsed/Refractory Primary Testicular Lymphoma (PTL)

Study ID: NCT02857426

Conditions

Lymphoma

Interventions

Nivolumab

Study Description

Brief Summary: The purpose of this study is to determine whether Nivolumab is effective in the treatment of Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Alabama at Birmingham, Birmingham, Alabama, United States

City Of Hope Medical Center, Duarte, California, United States

Mayo Clinic Jacksonville, Jacksonville, Florida, United States

H. Lee Moffitt Cancer Center & Research Inst, Inc, Tampa, Florida, United States

Dana Farber Cancer Institute, Boston, Massachusetts, United States

Massachusetts General Hospital, Boston, Massachusetts, United States

Karmanos Cancer Institute, Detroit, Michigan, United States

Mayo Clinic Rochester, Rochester, Minnesota, United States

Hackensack University Medical Center, Hackensack, New Jersey, United States

Columbia University, New York, New York, United States

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

Baylor Research Institute, Dallas, Texas, United States

Swedish Medical Center, Seattle, Washington, United States

Instituto Do Cancer Mae De Deus / Cor Hospital Mae De Deus, Porto Alegre, Rio Grande Do Sul, Brazil

Fundacao Pio Xii Hosp Cancer De Barretos, Barretos, Sao Paulo, Brazil

Hospital Das Clinicas - Fmusp, Sao Paulo, , Brazil

BC Cancer Agency - Vancouver Centre, Vancouver, British Columbia, Canada

Princess Margaret Cancer Centre, Toronto, Ontario, Canada

CHU de Quebec, Quebec, , Canada

I. interni klinika - klinika hematologie 1. LF UK a VFN v Praze, Praha 2, , Czechia

Local Institution, Bordeaux, , France

Local Institution, Caen, , France

Local Institution, La Tronche, , France

Local Institution, Lille Cedex, , France

Local Institution, Paris cedex 13, , France

Centre Hospitalier Lyon Sud - UPCO, Pierre Benite, , France

Local Institution, Rennes Cedex 9, , France

Local Institution, St. Cloud, , France

Local Institution, Tours Cedex 9, , France

Klinikum Stuttgart, Stuttgart, , Germany

Local Institution, Hong Kong, , Hong Kong

Local Institution, Budapest, , Hungary

Belgyogyaszati Onkologia OOI, Budapest, , Hungary

Local Institution, Debrecen, , Hungary

Local Institution, Haifa, , Israel

Local Institution, Jerusalem, , Israel

Local Institution, Petah Tikva, , Israel

Local Institution, Tel Aviv, , Israel

Irccs Ospedale S. Raffaele, Milano, , Italy

Fondazione Policlinico Universitario A. Gemelli, Roma, , Italy

Istituto Clinico Humanitas, Rozzano (milano), , Italy

Local Institution, Nagoya, Aichi, Japan

Local Institution, Fukuoka-shi, Fukuoka, Japan

Local Institution, Hidaka-shi, Saitama, Japan

Local Institution, Chuo-ku, Tokyo, Japan

Local Institution, Kotoku, Tokyo, Japan

Local Institution, Mitaka-shi, Tokyo, Japan

Local Institution, Yamagata, , Japan

Local Institution, Moscow, , Russian Federation

Local Institution, Singapore, , Singapore

Contact Details

Name: Bristol-Myers Squibb

Affiliation: Bristol-Myers Squibb

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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