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Brief Title: A Phase 2 Safety and Efficacy Study of INCB050465 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (CITADEL-202)
Official Title: A Phase 2, Multicenter, International, Open-Label, Safety and Efficacy Study of INCB050465 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (CITADEL-202)
Study ID: NCT02998476
Brief Summary: The purpose of this study is to assess the safety and efficacy of parsaclisib in subjects with relapsed or refractory diffuse large B-cell lymphoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Alabama at Birmingham, Birmingham, Alabama, United States
Banner MD Anderson Cancer Center, Gilbert, Arizona, United States
Arizona Oncology Associates, PC - HAL, Tempe, Arizona, United States
Sutter Gould Medical Foundation, Modesto, California, United States
Sharp Memorial Hospital, San Diego, California, United States
Advanced Pharma CR, LLC, Miami, Florida, United States
Asclepes Research Centers, Weeki Wachee, Florida, United States
Advocate Medical Group Niles Milwaukee Ave, Niles, Illinois, United States
Indiana BMT, Beech Grove, Indiana, United States
Parkview Research Center, Fort Wayne, Indiana, United States
University of Kentucky Hospital, Lexington, Kentucky, United States
St. Agnes Hospital, Baltimore, Maryland, United States
Karmanos Cancer Institute, Detroit, Michigan, United States
St. John Hospital and Medical Center, Detroit, Michigan, United States
CHI Health - St. Francis Medical Center, Grand Island, Nebraska, United States
Summit Medical Group, Morristown, New Jersey, United States
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States
Clinical Research Alliance, Lake Success, New York, United States
Abington Memorial Hospital, Abington, Pennsylvania, United States
Utah Cancer Specialists- Network, Salt Lake City, Utah, United States
St Vincent's Hospital Sydney, Darlinghurst, New South Wales, Australia
Westmead Hospital, Westmead, New South Wales, Australia
Flinders Medical Centre, Bedford Park, South Australia, Australia
Ballarat Base Hospital, Ballarat, Victoria, Australia
Sunshine Hospital, St Albans, Victoria, Australia
Fiona Stanley Hospital, Murdoch, Western Australia, Australia
ZNA Stuivenberg, Antwerpen, , Belgium
Cliniques Universitaires Ucl Saint-Luc, Brussels, , Belgium
UZ Leuven, Leuven, , Belgium
AZ Delta, Roeselare, , Belgium
LHSC - Victoria Hospital, London, Ontario, Canada
Fakultni nemocnice Brno, Brno, , Czechia
Fakultni nemocnice Hradec Kralove, Hradec Kralove, , Czechia
University Hospital Ostrava, Ostrava, , Czechia
Fakultni nemocnice v Motole, Praha 5, , Czechia
Centre Antoine Lacassagne, Nice cedex 02, Alpes Maritimes, France
Centre Francois Baclesse, Caen Cedex 05, Calvados, France
CHU Dijon - Hopital du Bocage, Dijon cedex, Cote dÝOr, France
Centre Hospitalier Libourne, Libourne Cedex, Gironde, France
CHU de Grenoble - Hôpital Albert Michallon, Grenoble, Isere, France
Centre Hospitalier d'Angers, Angers Cedex 01, Maine Et Loire, France
Hopital Claude Huriez - CHU Lille, Lille cedex, Nord, France
Hôpital Saint-Louis, Paris cedex 10, Paris, France
Clinique Victor Hugo - Centre Jean Bernard, Le Mans Cedex 02, Sarthe, France
Hôpital Henri Mondor, Créteil Cedex, Val De Marne, France
Chu de Grenoble - Hopital Albert Michallon, Grenoble, , France
Groupe Hospitalier Pitie-Salpetriere, Paris, , France
Chu Vandoeuvre-Les-Nancy Hopital Brabois, Vandoeuvre-les-nancy, , France
Institut Gustave Roussy, Villejuif Cedex, , France
IRCCS Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy
Istituto Tumori Giovanni Paolo II IRCCS Ospedale Oncologico Bari, Bari, , Italy
Istituto Scientifico Romagnolo Per Lo Studio E La Cura Dei Tumori, Meldola, , Italy
Policlinico Universitario Agostino Gemelli Universita Cattolica Del Sacro Cuore, Rome, , Italy
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital, Yonsei University, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Szpital Specjalistyczny W Brzozowie, Podkarpacki Osrodek Onkologiczny Im.Ks.B.Markiewicza, Brzozów, , Poland
Uniwersyteckie Centrum Kliniczne, Gdansk, , Poland
Malopolskie Centrum Medyczne s.c., Krakow, , Poland
ICO l´Hospitalet - Hospital Duran i Reynals, L'Hospitalet de llobregat, Barcelona, Spain
Hospital del Mar, Barcelona, , Spain
Hospital General Universitario Gregorio Marañon, Madrid, , Spain
Hospital Universitario Ramon y Cajal, Madrid, , Spain
Clinica Universidad de Navarra (Cun), Pamplona, , Spain
Hospital Universitario Nuestra Señora de Valme, Sevilla, , Spain
Hospital Txagorritxu, Vitoria, , Spain
The Christie, Manchester, Greater Manchester, United Kingdom
Southend University Hospital, Southend-on-sea, , United Kingdom
Royal Marsden Hospital, Sutton, , United Kingdom
Name: Claudia Corrado, MD
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR