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Brief Title: Study of ACTR707 in Combination With Rituximab in Subjects With Relapsed or Refractory B Cell Lymphoma
Official Title: Phase 1 Study of ACTR707, an Autologous T Cell Product, in Combination With Rituximab, in Subjects With Relapsed or Refractory CD20+ B Cell Lymphoma
Study ID: NCT03189836
Brief Summary: This is a phase 1, multi-center, single-arm, open-label study evaluating the safety and anti-lymphoma activity of an autologous T cell product (ACTR707) in combination with rituximab in subjects with refractory or relapsed CD20+ B cell lymphoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Banner MD Anderson Cancer Center, Gilbert, Arizona, United States
Yale University, New Haven, Connecticut, United States
Emory University, Winship Cancer Institute, Atlanta, Georgia, United States
Loyola University, Maywood, Illinois, United States
Indiana Bone and Marrow Transplantation, Indianapolis, Indiana, United States
University of Maryland, Baltimore, Maryland, United States
University of Minnesota, Minneapolis, Minnesota, United States
Ohio State University, Columbus, Ohio, United States
Tennessee Oncology - Nashville, Nashville, Tennessee, United States
The University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Name: Jessica Sachs, MD
Affiliation: Cogent Biosciences, Inc.
Role: STUDY_DIRECTOR