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Brief Title: Phase I, Open-label, Dose Escalation of AZD4877 in Hematologic Malignancies
Official Title: A Phase I, Open-label, Dose Escalation Study to Assess the Safety, Tolerability & Pharmacokinetics of AZD4877 Administered Once Weekly in Adult Patients With Recurrent or Refractory AML, PH Negative ALL, NHL or MN
Study ID: NCT00460460
Brief Summary: The primary purpose of this study is to find out what the maximum tolerated dose is for an experimental drug called AZD4877 based on the side effects experienced by patients that receive AZD4877 on a weekly basis in these diseases.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Research site, Buffalo, New York, United States
Research Site, New York, New York, United States
Research Site, Toronto, Ontario, Canada
Name: Judith Ochs, MD
Affiliation: AstraZeneca
Role: STUDY_DIRECTOR