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Brief Title: A Study of Itacitinib (INCB039110) in Combination With Ibrutinib in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Official Title: An Open-Label Phase 1/2 Study of Itacitinib (INCB039110) in Combination With Ibrutinib in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Study ID: NCT02760485
Brief Summary: The purpose of this study is to evaluate the safety/tolerability and efficacy of itacitinib in combination with ibrutinib in subjects with relapsed or refractory diffuse large B-cell lymphoma (DLBCL)
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Mayo Clinic Arizona, Scottsdale, Arizona, United States
City of Hope National Medical Center, Duarte, California, United States
Pacific Shores Medical Group, Long Beach, California, United States
LAC-USC Medical Center/Kenneth Norris Jr Cancer Hospital, Los Angeles, California, United States
Moores UC San Diego Cancer Center, San Diego, California, United States
Mount Sinai Comprehensive Cancer Center, Miami Beach, Florida, United States
Georgia Regents Research Institute, Augusta, Georgia, United States
University of Maryland Cancer Center, Baltimore, Maryland, United States
University of Michigan Cancer Center, Ann Arbor, Michigan, United States
Michigan State University Breslin Cancer Center, Lansing, Michigan, United States
St Vincent Frontier Cancer Center, Billings, Montana, United States
Comprehensive Cancer Center of Nevada, Las Vegas, Nevada, United States
Regional Cancer Center Associates, LLC, Little Silver, New Jersey, United States
Roswell Cancer Center, Buffalo, New York, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
Toledo Clinic Cancer Centers, Toledo, Ohio, United States
Tulsa Cancer Center, Tulsa, Oklahoma, United States
Geisinger Medical Center, Danville, Pennsylvania, United States
University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States
Houston Methodist Cancer Center, Houston, Texas, United States
Northwest Medical Specialists & Research Institute, Puyallup, Washington, United States
Name: Peter Langmuir, MD
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR