Spots Global Cancer Trial Database for Improving Hepatocellular Carcinoma Screening
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Trial Identification
Brief Title: Improving Hepatocellular Carcinoma Screening
Official Title: Prospective Comparison of Diagnostic Performance and Cost-effectiveness of US and Abbreviated MRI for Hepatocellular Carcinoma Screening
Study ID: NCT05828446
Interventions
Study Description
Brief Summary: This is a monocentric, single blind, interventional, single arm study. It is designed to compare the rates of detection of hepatocellular carcinoma (HCC) by ultrasound (US) used in clinical routine vs. abbreviated magnetic resonance imaging (AMRI). The hypothesis is that dynamic AMRI with extracellular contrast agent injection has a higher patient-level detection rate of HCC than screening US and non-contrast AMRI. Interested and eligible patients will be enrolled and undergo HCC screening rounds including US +/- contrast-enhanced US (clinical routine) and screening MRI within the same week bi-annually.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Lausanne University Hospital, Lausanne, Vaud, Switzerland
Contact Details
Name: Naik Vietti Violi, MD
Affiliation: Lausanne University Hospital
Role: PRINCIPAL_INVESTIGATOR
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