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Brief Title: High Dose Camptothecin-11 (CPT-11) in Recurrent Unresectable Malignant Glioma
Official Title: Phase I/II Study of High Dose Irinotecan (Camptosar, CPT-11) in Patients With Recurrent Unresectable Malignant Glioma on Steroids/Anti-epileptics
Study ID: NCT00283556
Brief Summary: The purpose of this study is to compare the response to treatment and side effects associated with high dose irinotecan in patients with recurrent brain tumors.
Detailed Description: This is a phase I/II study of high dose irinotecan in patients with recurrent unresectable malignant glioma on steroids/anti-epileptics. The purpose is to compare the response to treatment and side effects associated with high dose irinotecan in patients with recurrent brain tumors.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Kentuckiana Cancer Institute, Louisville, Kentucky, United States
Name: Renato V. LaRocca, MD
Affiliation: Director
Role: PRINCIPAL_INVESTIGATOR