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Brief Title: A Study of DEDN6526A in Patients With Metastatic or Unresectable Melanoma
Official Title: A Phase I, Open-Label Study of the Safety and Pharmacokinetics of Escalating Doses of DEDN6526A in Patients With Metastatic or Unresectable Melanoma
Study ID: NCT01522664
Brief Summary: This multicenter, open-label study will assess the safety and pharmacokinetics of DEDN6526A in patients with metastatic or unresectable melanoma. Cohorts of patients will receive escalating doses of DEDN6526A by intravenous infusion on Day 1 of each 21-day cycle. In the absence of disease progression or unacceptable toxicity, patients may continue to receive DEDN6552A for up to 17 cycles (1 year).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Los Angeles, California, United States
, Sarasota, Florida, United States
, Detroit, Michigan, United States
, Nashville, Tennessee, United States
, Camperdown, New South Wales, Australia
, East Melbourne, Victoria, Australia
Name: Clinical Trials
Affiliation: Genentech, Inc.
Role: STUDY_DIRECTOR