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Brief Title: Chloroquine in Combination With Carboplatin/Gemcitabine in Advanced Solid Tumors
Official Title: A Phase 1 Study of Chloroquine in Combination With Carboplatin/Gemcitabine in Advanced Solid Tumors
Study ID: NCT02071537
Brief Summary: The purpose of this research study is to test the safety of chloroquine in combination with carboplatin and gemcitabine and see what effects (good and bad) it has on advanced solid tumors. Also, the research study will be increasing the dose of chloroquine to find the highest dose of chloroquine that can be given in combination with carboplatin and gemcitabine without causing severe side effects.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Cincinnati Cancer Institute, Cincinnati, Ohio, United States
Name: Nagla Abdel-Karim, MD
Affiliation: University of Cincinnati
Role: PRINCIPAL_INVESTIGATOR