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Spots Global Cancer Trial Database for Short-term Psychodynamic Psychotherapy in Serious Physical Illness

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Trial Identification

Brief Title: Short-term Psychodynamic Psychotherapy in Serious Physical Illness

Official Title: ORPHYS - Short-term Psychodynamic Psychotherapy in Serious Physical Illness

Study ID: NCT05520281

Study Description

Brief Summary: Life-threatening physical illness may powerfully re-activate existential conflict. There is little evidence to date on the effectiveness of relationship-focused therapies in this patient group.The aim of this study is to pilot a psychodynamic treatment for patients with advanced cancer and high psychological distress.

Detailed Description: Severely physically ill patients may experience existential distress symptoms including helplessness, hopelessness, death anxiety, perceived burdensomeness and a sense of pointlessness. The latter can significantly interfere with end-of-life care processes and outcomes (receipt of treatment according to preferences, expression of desire for hastened death). So far, empirically tested psychotherapeutic programs in advanced life-threatening illness have predominantly been ultra-short and applied supportive and resource-oriented techniques. Psychodynamic treatment allows to address clinically significant existential distress through its conceptualization from early relational life experiences. The aim of this study is to pilot a psychodynamic treatment for patients with advanced cancer and high psychological distress.The inverstigators will 1. analyse the feasibility of the treatment, and 2. investigate changes in process- and patient-relevant outcomes over the course of the treatment The inverstigators will conduct a single-group pre-post study with five assessment points in which 50 adult patients diagnosed with advanced cancer will receive a manualized psychodynamic short-term therapy. Target parameters are assessed by diagnostic interviews, focus interviews, self-assessment questionnaires as well as electronic patient records. For research objective b) the investigators will compare the intervention group with a matched comparison group of a longitudinal cohort sample (NCT04600206). Matching will be based on stress level, demographic, and medical parameters across the 5 assessment points.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Clinical Institute for Psychosomatic Medicine and Psychotherapy, University Medical Center Düsseldorf, Düsseldorf, , Germany

University Medical Center Hamburg Eppendorf, Department of Medical Psychology, Hamburg, , Germany

Institute of Social Work, University of Kassel, Kassel, , Germany

Psychosomatics, Psychotherapy and Psychooncology, Medicine II, University of Würzburg, Würzburg, , Germany

Contact Details

Name: Sigrun Vehling, PD, PhD

Affiliation: Universitätsklinikum Hamburg-Eppendorf

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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