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Brief Title: PM8002 in the Treatment of Patients With Advanced Solid Tumors
Official Title: Phase Ib/IIa Safety and Efficacy of PM8002, a Bispecific Antibody Targeting PD-L1 and VEGF-A, as a Monotherapy in Patients With Advanced Solid Tumors
Study ID: NCT05918445
Brief Summary: This study is to characterize the safety, tolerability, pharmacokinetics (PK), immunogenicity, pharmacodynamics (PD) and anti-tumor activity of PM8002, a PD-L1/VEGF bispecific antibody, as a single agent in adult subjects with advanced solid tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Shanghai Orient Hospital, Shanghai, Shanghai, China
Name: YE GUO
Affiliation: Shanghai Orient Hospital
Role: PRINCIPAL_INVESTIGATOR