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Brief Title: Study of Carboplatin and Vinorelbine in Malignant Pleural Mesothelioma
Official Title: Phase II Study of Carboplatin and Vinorelbine i.v. (Day 1) and Orally (Day 8) for Malignant Pleural Mesothelioma
Study ID: NCT00272558
Brief Summary: The purpose is to evaluate the activity and feasibility of a two drug regimen which is partly orally and partly intravenous in advanced pleural mesothelioma.
Detailed Description: Chemotherapy with carboplatin i.v. day one in each cycle Vinorelbine i.v. day one, and orally day 8 in each cycle, repeat new cycle every 3 weeks. Total of 6 cycles. Endpoint is response rate, secondary endpoints survival and toxicity.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Dept. Oncol., Rigshospitalet, Copenhagen, , Denmark
Name: Jens B Sorensen, MD
Affiliation: Dept. Oncology, Rigshospitalet
Role: STUDY_CHAIR